Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2007-08-14
2007-08-14
Graser, Jennifer E. (Department: 1645)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S024100, C536S024200, C536S024320, C435S320100
Reexamination Certificate
active
11445045
ABSTRACT:
The present invention provides novel isolated nucleic acids encoding antigenic proteins derived fromSarcocystis neurona, or unique fragments thereof. In particular, the invention provides novel isolated nucleic acids encoding membrane-associated polypeptides SnSAG2, SnSAG3, and SnSAG4. Also provided are purified antigenic polypeptide fragments encoded by the novel nucleic acid sequences set forth herein that encode for SnSAG2, SnSAG3, and SnSAG4. Also provided are isolated nucleic acids capable of selectively hybridizing with the nucleic acid fromSarcocystis neurona. The invention also provides vectors comprising the nucleic acids of the invention encoding an antigenic protein derived fromSarcocystis neuronaor a unique fragment thereof and provides the vector in a host capable of expressing the polypeptide encoded by that nucleic acid. Finally, the invention provides purified polyclonal and/or monoclonal antibodies specifically reactive withSarcocystis neuronaand a method of detection ofSarcocystis neuronautilizing the antibodies of the invention.
REFERENCES:
patent: 6808714 (2004-10-01), Dame et al.
Mikayama et al. (Nov. 1993. Proc.Natl.Acad.Sci. USA, vol. 90 : 10056-10060).
Rudinger et al. (Jun. 1976. Peptide Hormones. Biol. Council. pp. 5-7).
Graser Jennifer E.
King & Schickli PLLC
University of Kentucky Research Foundation
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