Nucleic acids encoding respiratory syncytial virus subgroup...

Details Nucleic acids encoding respiratory syncytial virus subgroup... Nucleic acids encoding respiratory syncytial virus subgroup...

2004-03-26

2009-08-11

Chen, Stacy B (Department: 1648)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C424S211100

Reexamination Certificate

active

07572904

ABSTRACT:
The complete polynucleotide sequence of the human respiratory syncytial virus subgroup B strain 9320 genome is provided. Proteins encoded by this polynucleotide sequence are also provided. Isolated or recombinant RSV (e.g., attenuated recombinant RSV), nucleic acids, and polypeptides, e.g., comprising mutations in the attachment protein G, are also provided, as are immunogenic compositions comprising such isolated or recombinant RSV, nucleic acids, and polypeptides. Related methods are also described.

REFERENCES:
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patent: WO 02/44334 (2002-06-01), None
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patent: WO 2004/028478 (2004-04-01), None
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GenBank accession No. M73544.
GenBank accession No. S75820.
GenBank accession No. D00334.
GenBank accession No. D00392.
GenBank accession No. D00393.
GenBank accession No. D00394.
GenBank accession No. D00395.
GenBank accession No. D00396.
GenBank accession No. D00397.
GenBank accession No. D00736.
GenBank accession No. D01042.
GenBank accession No. M17213.
GenBank accession No. AF013254.
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Fearns et al., 2000, “Functional Analysis of the Genomic and Antigenomic Promoters of Human Respiratory Syncytial Virus.” J. Virol. 74(13):6006-6014.
Garcia et al., 1994, “Evolutionary pattern of human respiratory syncytial virus (subgroup A): cocirculating lineages and correlation of genetic and antigenic changes in the G glycoprotein.” J. Virol. 68(9):5448-5459.
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Zimmer et al., 2002, “Cleavage at the furin consensus sequence RAR/KR(109) and presence of the intervening peptide of the respiratory syncytial virus fusion protein are dispensable for virus replication in cell culture.” J. Virol. 76(18):9218-9224.
Database UniProt Mar. 1, 2002, XP002407584 retrieved from EBI Database accession No. Q8V220.
Database UniProt Mar. 1, 2001, XP002407585 retrieved from EBI Database accession No. Q9DH68.
Database UniProt Mar. 1, 1992, XP002407586 retrieved from EBI Database accession No. P24566.
GenBank accession No. M73544, downloaded Dec. 7, 2004.
GenBank accession No. S75820, downloaded Dec. 7, 2004.
GenBank accession No. D00334, downloaded Dec. 7, 2004.
GenBank accession No. D00392, downloaded Dec. 7, 2004.
GenBank accession No. D00393, downloaded Dec. 7, 2004.
GenBank accession No. D00394, downloaded Dec. 7, 2004.
GenBank accession No. D00395, downloaded Dec. 7, 2004.
GenBank accession No. D00396, downloaded Dec. 7, 2004.
GenBank accession No. D00397, downloaded Dec. 7, 2004.
GenBank accession No. D00736, downloaded Dec. 7, 2004.
GenBank accession No. D01042, downloaded Dec. 7, 2004.
GenBank accession No. M17213, downloaded Dec. 7, 2004.
GenBank accession No. AF013254, downloaded Dec. 7, 2004.

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