Nucleic acids encoding P-selectin ligand fusion proteins

Details Nucleic acids encoding P-selectin ligand fusion proteins Nucleic acids encoding P-selectin ligand fusion proteins

2011-04-19

2011-04-19

Kemmerer, Elizabeth C. (Department: 1646)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C536S023100, C536S023400, C536S023500, C536S024100

Reexamination Certificate

active

07927835

ABSTRACT:
A novel P-selectin ligand glycoprotein is disclosed, comprising the amino acid sequence set forth in SEQ ID NO:2 or by the amino acid sequence set forth in SEQ ID NO:4. DNA sequences encoding the P-selectin ligand protein are also disclosed, along with vectors, host cells, and methods of making the P-selectin ligand protein. Pharmaceutical compositions containing the P-selectin ligand protein and methods of treating inflammatory disease states characterized by P-selectin- and E-selectin-mediated intercellular adhesion are also disclosed.

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