Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2008-07-01
2008-07-01
Saoud, Christine J (Department: 1647)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S069400, C435S069700, C435S243000, C435S320100, C435S325000
Reexamination Certificate
active
11132814
ABSTRACT:
The present invention relates to the field of obesity research. Obesity is a public health problem that is serious and widespread. This application pertains to nucleic acids encoding a compound, globular OBG3 polypeptide fragments, vectors and transformed host cells containing these nucleic acids and methods of making the globular OBG3 polypeptide fragments.
REFERENCES:
patent: 5270170 (1993-12-01), Schatz et al.
patent: 5635373 (1997-06-01), Wozney et al.
patent: 5869330 (1999-02-01), Scherer et al.
patent: 6126939 (2000-10-01), Eisenbach-Swartz et al.
patent: 6197930 (2001-03-01), Sheppard et al.
patent: 6344441 (2002-02-01), Bihain et al.
patent: 6635431 (2003-10-01), Bihain et al.
patent: 2002/0151498 (2002-10-01), Bihain et al.
patent: 2002/0165154 (2002-11-01), Bihain et al.
patent: 2004/0077051 (2004-04-01), Bihain et al.
patent: 2005/0059631 (2005-03-01), Fruebis et al.
patent: 1033134 (2000-09-01), None
patent: WO 96/30400 (1996-10-01), None
patent: WO 96/34981 (1996-11-01), None
patent: WO 96/39429 (1996-12-01), None
patent: WO 97/27288 (1997-07-01), None
patent: WO 98/01257 (1998-01-01), None
patent: WO 98/20165 (1998-05-01), None
patent: WO 98/54311 (1998-12-01), None
patent: WO 99/07736 (1999-02-01), None
patent: WO 99/07737 (1999-02-01), None
patent: WO 99/07738 (1999-02-01), None
patent: WO 99/10492 (1999-03-01), None
patent: WO 99/21577 (1999-05-01), None
Wang et al. (Nuc. Acids Res. 27: 4609-4618, 1999.
Kaufman et al (Blood 94: 3178-3184, 1999).
Phillips, A., J Pharm Pharmacology 53: 1169-1174, 2001.
Alexeev, V. and Yoon, K. “Stable and Inheritable Changes in Genotype and Phenotype of Albino Melanocytes Induced by an RNA-DNA Oligonculeotide”Nature Biotech, 1998, pp. 1343-1346, vol. 16.
Arita, Y. et al. “Paradoxical Decrease of an Adipose-Specific Protein, Adiponectin, in Obesity”Biochem. and Biophys. Research Comm., 1999, pp. 79-83, vol. 257 (Academic Press).
Austin, M.A. et al. “Hypertriglyceridemia as a Cardiovascular Risk Factor”Am. J. Cardiol., 1998, pp. 7B-12B, vol. 81, No. 4A (Excerpta Medica, Inc.).
Baldo, A. et al. “The Adipsin-Acylation Stimulating Protein System and Regulation of Intracellular Triglyceride Synthesis”J. Clin. Invest., Sep. 1993, pp. 1543-1547, vol. 92 (The American Society for Clinical Investigation, Inc.).
Bartles, J.R. et al. “Biogenesis of the Rat Hepatocyte Plasma Membrane”Methods Enzymol, 1990, pp. 825-841, vol. 191 (Academic Press).
Bihain, B.E. et al. “Characterization and Purification of the Lipolysis-Stimulated Receptor” 1995, pp. 465-470, Elsevier Science B.V.
Bihain, B.E. et al. “Free Fatty Acids Activate a High-Affinity Saturable Pathway for Degradation of Low-Density Lipoproteins in Fibroblasts from a Subject Homozygous for Familial Hypercholesterolemia”Biochemistry, 1992, pp. 4628-4636, vol. 31 (American Chemical Society).
Brendel, V. et al. “Methods for Algorithms for Statistical Analysis of Protein Sequences”Proc. Natl. Acad. Sci. USA, Mar. 1992, pp. 2002-2006, vol. 89.
Chen, W.J. et al. “NPXY, a Sequence often Found in Cytoplasmic Tails, is Required for Coated Pit-Mediated Internalization of the Low Density Lipoprotein Receptor”J. Biol. Chem, Feb. 25, 1990, pp. 3116-3123, vol. 265 (The American Society for Biochemistry and Molecular Biology, Inc.).
Cole-Strauss, A. et al. “Correction of the Mutation Responsible for Sickle Cell Anemia by an RNA-DNA Oligonculeotide”Science, Sep. 6, 1996, pp. 1386-1389, vol. 273.
Costet, P. et al. “Peroxisome Proliferator-Activated Receptor α-isoform Deficiency Leads to Progressive Dyslipidemia with Sexually Dimorohic Obesity and Steatosis”J. Biol. Chem., Nov. 6, 1998, pp. 29577-29585, vol. 273, No. 45 (The American Society for Biochemistry and Molecular Biology, Inc.).
Davis, C.G. et al. “The J.D. Mutation in Familial Hypercholesterolemia: Amino Acid Substitution in Cytoplasmic Domain Impedes Internatization of LDL Receptors”Cell, Apr. 11, 1986, pp. 15-24, vol. 45 (Cell Press).
Everhart, J.E. et al. “Weight Change and Obesity After Liver Transplantation: Incidence and Risk Factors”Liver Transpl. Surg., Jul. 1998, pp. 285-296, vol. 4, No. 4.
Feeman, Jr., W.E. et al. “Hypertriglyceridemia and Atherosclerosis”Annals of Internal Medicine, 1998, pp. 73-74, vol. 128, No. 1.
Ghebrehiwet, B. et al. “Isolation, cDNA Cloning, and Overexpression of a 33-kD Cell Surface Glycoprotein that Binds to the Globular ‘Heads’ of C1q”J. Exp. Med., Jun. 1994, pp. 1809-1821, vol. 179 (The Rockefeller University Press).
Goldstein, J.L. et al. “Familial Hypercholesterolemia”The Metabolic and Molecular Bases of Inherited Disease, 1995, pp. 1981-2030, vol. II, 7th Edition, ed. Scriver, C.R. et al., McGraw-Hill, New York.
Goldstein, J.L. et al. “Hyperlipidemia in Coronary Heart Disease”J. Clin. Invest., Jul. 1973, pp. 1533-1543, vol. 52.
Gura, T. et al. “Obesity Sheds its Secrets”Science, Feb. 7, 1997, pp. 751-753, vol. 275.
Hayward, C.P. et al. “The cDNA Sequence of Human Endothelial Cell Multimerin”J. Biol. Chem., Aug. 4, 1995, pp. 18246-18251, vol. 270, No. 31 (The American Society for Biochemistry and Molecular Biology, Inc.).
Henrion, A.A. et al. “Structure, Sequence, and Chromosomal Location of the Gene for USF2 Transcription Factors in Mouse”Genomics, 1995, pp. 36-43, vol. 25 (Academic Press, Inc.).
Herz, J. et al. “Surface Locations and High Affinity for Calcium of a 500-kd Liver Membrane Protein Closely Related to the LDL-Receptor Suggest a Physiological Role as Lipoprotein Receptor”European Molecular Biology Laboratory, 1988, pp. 4119-4127, vol. 7 (IRL Press Limited, Oxford, England).
Honore, B. et al. “Cloning and Expression of a cDNA Covering the Complete Coding Region of the P32 Subunit of Human Pre-mRNA Splicing Factor SF2”Gene, 1993, pp. 283-287, vol. 134 (Elsevier Science Publishers B.V.).
Hu, E. et al. “AdipoQ is a Novel Adipose-Specific Gene Dysregulated in Obesity”J. Biol. Chem., May 3, 1996, pp. 10697-10703, vol. 271, No. 18.
Huettinger, M. et al. “Characteristics of Chylomicron Remnant Uptake into Rat Liver”Clin. Biochem., 1988, pp. 87-92 vol. 21.
Imagawa, K. et al. “Structure-Function Studies of Human Leptin”J. Biol. Chem., Dec. 25, 1998, pp. 35245-35249, vol. 273, No. 52 (The American Society for Biochemistry and Molecular Biology, Inc.).
Karpe, F. et al. “Clearance of Lipoprotein Remnant Particles in Adipose Tissue and Muscle in Humans”J. Lipid Res., 1997, pp. 2335-2343, vol. 38.
Karpe, F. et al. “Magnitude of Alimentary Lipema is Related to Intima-media Thickness of the Common Carotid Artery in Middle-Aged Men”Atherosclerosis, 1998, pp. 307-314, vol. 141.
Kersten, S. et al. “Peroxisome Proliferator-Activated Receptor α Mediates The Adaptive Response of Fasting”J. Clin. Invest., Jun. 1999, pp. 1489-1498, vol. 103, No. 11 (The Amercian Society for Clinical Investigations).
Khallou et al. “Correction of Delayed Postprandial Plasma Lipid Response in Genetically Obese Mice by Injection of Recombinant Lectin” Abstract from the 69th Scientific Sessions, New Olreans, LA; Supplemental toCirculation, American Heart Association, 1996, p. 8, vol. 94.
Krainer, A.R. et al. “Functional Expression of Cloned Human Splicing Factor SF2: Homology to RNA-Binding Proteins, U1 70K, andDrosophiaSplicing Regulators”Cell, Jul. 26, 1991, pp. 383-394, vol. 66 (Cell Press).
Lee, M.G.-S. et al. “Characterization of a cDNA Encoding a Cysteine-Rich Cell Surface Protein Located in the Flagellar Pocket of the ProtozoanTrypanosoma brucei” Molec. Cell. Biol., Sep. 1990, pp. 4506-4517, vol. 10 (American Society for Microbiology).
Letourneur, F.. et al. “A Novel Di-Leucine Motif and a Tyrosine-Based Motif Independently Mediate Lysosomal Targeting and Endocytosis of CD3
Bihain Bernard
Erickson Mary Ruth
Fruebis Joachim
Yen-Potin Frances
Saliwanchik, Lloyd & Sliwanchik
Saoud Christine J
Serono Genetics Institute S.A.
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