Nucleic acids encoding nuclear Dbf2-related (Ndr) kinases

Details Nucleic acids encoding nuclear Dbf2-related (Ndr) kinases Nucleic acids encoding nuclear Dbf2-related (Ndr) kinases

1999-06-22

2000-03-21

Carlson, Karen Cochrane

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Oxidoreductase

435183, 435 691, 4353201, 4352523, 435325, C12N 902, C12N 1500, C12P 2106

Patent

active

060401648

ABSTRACT:
The current invention describes the identification of a novel widely-expressed human and D. melanogaster serine/threonine protein kinase (designated nuclear, Dbf2-related kinase, or Ndr; previously referred to as Ndr) and the use of this kinase for the identification of agonists and antagonists. The kinase is a nuclear protein and contains a short basic peptide, KRKAETWKRNRR, responsible for the nuclear accumulation.

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