Nucleic acids encoding non-aggregating fluorescent proteins...

Details Nucleic acids encoding non-aggregating fluorescent proteins... Nucleic acids encoding non-aggregating fluorescent proteins...

2006-12-19

2006-12-19

Robinson, Hope (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S006120, C435S069100, C435S320100, C435S325000, C435S007100, C435S810000, C530S350000

Reexamination Certificate

active

07150979

ABSTRACT:
Nucleic acid compositions encoding non-aggregating chromo/fluoroproteins and mutants thereof, as well as the encoded proteins, are provided. The proteins of interest are polypeptides that are non-aggregating colored and/or fluorescent proteins, where the non-aggregating feature arises from the modulation of residues in the N-terminus of the protein and the chromo and/or fluorescent feature arises from the interaction of two or more residues of the protein. Also provided are fragments of the subject nucleic acids and the peptides encoded thereby, as well as antibodies to the subject proteins and transgenic cells and organisms. The subject protein and nucleic acid compositions find use in a variety of different applications. Finally, kits for use in such applications, e.g., that include the subject nucleic acid compositions, are provided.

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