Nucleic acids encoding mutated human immunodeficiency virus matr

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

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4353201, 536 2372, 514 44, 424 931, 424 932, 424 9321, 930221, C12N 1549, C12N 510, C12N 1563, C07K 14155

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active

057078645

ABSTRACT:
Nucleic acid constructs encoding mutated human immunodeficiency virus matrix proteins are described. The mutated proteins lower the incorporation of envelope polypeptides in viral particles, disrupt viral assembly or disrupt viral entry into uninfected cells.

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