Nucleic acids encoding merosin

Details Nucleic acids encoding merosin Nucleic acids encoding merosin

1993-09-22

1999-02-16

Loring, Susan A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 221, 536 235, 435 691, 435 693, 4353201, C07H 2102, C07H 1900, C12P 2106, C12N 1500

Patent

active

058722319

ABSTRACT:
This invention provides an isolated nucleic acid molecule encoding a subunit of a protein, the protein having an apparent molecular weight of about 800 kD, designated merosin. Also provided are isolated nucleic acid molecules which encode merosin fragments. Anti-merosin antibodies, vectors for the recombinant production of merosin, and the expression of recombinant proteins by use of a host vector system also are provided. The invention further provides the use of merosin to promote neurite growth and for certain diagnostic applications.

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