Nucleic acids encoding human prohibitin mutants and detection th

Details Nucleic acids encoding human prohibitin mutants and detection th Nucleic acids encoding human prohibitin mutants and detection th

1993-08-31

1995-03-28

Parr, Margaret

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 912, 4352402, 536 231, 536 235, 536 2351, 536 2433, C12Q 168, C12P 1934, C07H 2104

Patent

active

054016355

ABSTRACT:
A human prohibitin gene, a protein coded for by said gene, a gene analysis reagent to be used with them, and a quantitative determination of prohibitin in a biological sample by an immunological technique with the use of an antihuman prohibitin antibody and a method for analyzing a prohibitin gene of a human tissue for the occurrence of mutation by the PCR method with the use of oligonucleotides having partial base sequences of said gene as primers.

REFERENCES:
White et al., Genomics 11,228-230 (1991).
Sato et al., Cancer Research 52, 1643-1646 (Mar. 16, 1992).
Adams et al., Nature 355, 632-634 (Feb. 13, 1992).
Nuell et al., Mol. Cell. Biol. 11(3), 1372-1381 (Mar. 1991).
Lundwall, Bioch. Biophys. Res. Comm. 161(3), 1151-1159 (1989).

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