Nucleic acids encoding human coagulation factor VII variants

Details Nucleic acids encoding human coagulation factor VII variants Nucleic acids encoding human coagulation factor VII variants

2005-04-21

2008-08-26

Robinson, Hope A (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S320100, C435S006120, C435S252000

Reexamination Certificate

active

07416860

ABSTRACT:
The invention concerns nucleic acids encoding coagulation Factor VII variants in which the Leu residue in position 305 has been replaced by another amino acid residue. The invention further concerns the expression of such nucleic acids resulting in a Factor VII variant having increased biological activity.

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