Nucleic acids encoding human adamalysin SVPH1-8

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

Reexamination Certificate

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C435S004000, C435S006120, C435S069100, C435S183000, C435S200000, C435S252300, C435S320100, C435S325000, C536S023200, C536S023500, C536S023600, C536S023700, C530S350000

Reexamination Certificate

active

10265125

ABSTRACT:
The disclosure provides purified and isolated SVPH1–8 polypeptides, nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against such polypeptide, and fragmented peptides derived from these polypeptide. In addition, the disclosure provides uses of such polypeptides, fragmented peptides, antibodies and nucleic acids as well as kits containing the foregoing.

REFERENCES:
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patent: 9716755.5 (1997-10-01), None
patent: WO 99/07856 (1999-02-01), None
Perry et al. (Biochem. J. vol. 312:239-244, 1995 and GenBank Accession No. I6525337).
McKie et al. (Biochem. J. vol. 318:459-462, 1996 and GenBank Accession No. S71949).
Hooft Van Juijsduijnen, R., “ADAM 20 and 21; two novel human testis-specific membrane metalloproteases with similarity to fertilin-alpha”,Gene206(2): 273-282 (1998).
New England BioLabs Catalog 96/97, “Protein Molecular Weight Markers”.
Wolfsberg et al., The Journal of Cell Biology, 131(2):275-278 (1995).
Strausberg, National Cancer Institute, Cancer Genome Anatomy Project, EMBL Database Entry AA758110, Accession No. AA758110, (Jan. 26, 1998), XP002101680.
PubMed Abstract for Hooft Van Juijsduijnen, R., “ADAM 20 and 21; two novel human testis-specific membrane metalloproteases with similarity to fertilin-alpha”, Gene 1998 Jan. 12; 206(2):273-82.

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