Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2007-06-05
2007-06-05
Kunz, Gary (Department: 1647)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S325000, C435S252330, C435S320100, C536S023510, C536S023100
Reexamination Certificate
active
08182183
ABSTRACT:
A novel neurotrophic factor referred to as glial cell line-derived neurotrophic factor (GDNF) has been identified and isolated from serum free growth conditioned medium of B49 glioblastoma cells. Rat and human genes encoding GDNF have been cloned and sequenced. A gene encoding GDNF has been subcloned into a vector, and the vector has been used to transform a host cell in order to produce biologically active GDNF in a recombinant DNA process.
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Bektesh Susan
Collins Franklin D.
Doherty Daniel H.
Lile Jack
Lin Leu-Fen H.
Amgen Inc.
Hayes Robert C.
Kunz Gary
Levy Ron K.
Sharp Robert L.
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