Nucleic acids encoding dipeptidyl peptidases

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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Details

C435S226000, C435S252300, C435S252330, C435S320100, C435S325000, C435S006120

Reexamination Certificate

active

07148338

ABSTRACT:
The present invention provides nucleic acids that encodes a human dipeptidyl peptidase (DPP8), which shares structural and functional characteristics with dipeptidyl peptidase IV (DPPIV; CD26) and fibroblast activation protein (FAP). Vectors and cells comprising the nucleic acids are also disclosed.

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Abott et al, Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8, Eur J Biochem. Oct. 2000;267(20):6140-50.
EST database Accession No. AA496257 NCI-CGAP Aug. 18, 1997. Alignment with SEQ ID No. 2.
Qi, et al., Human DPPIV Related Serine Protease DPRP-1, from WO 200231134, Apr. 18, 2002, Seq.ABG61591, Alignment with SEQ ID No. 1.
Kawakami, et al., EMBL Acc# AK000290 alignment with SEQ ID No. 1, Feb. 22, 2000.
Database EMBL 'Online! retrieved from EMBL Database Accession No. AA417787; XP002266787 (Abstract).
Database EMBL 'Online! retrieved from EMBL Database Accession No. AA278625; XP002266788 (Abstract).
Database EMBL 'Online! retrieved from EMBL Database Accession No. AA496257; XP002266789 (Abstract).
UNIPROT Accession No. O75273 from the UNIPROT Protein Database.

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