Nucleic acids encoding B7-Like molecules and uses thereof

Details Nucleic acids encoding B7-Like molecules and uses thereof Nucleic acids encoding B7-Like molecules and uses thereof

2004-11-29

2008-08-19

Ouspenski, Ilia (Department: 1644)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S320100, C435S252300, C435S455000, C435S069100, C514S04400A

Reexamination Certificate

active

07414122

ABSTRACT:
The present invention provides B7-Like (B7-L) polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, and methods for producing B7-L polypeptides. The invention further provides pharmaceutical compositions and methods for the diagnosis, treatment, amelioration, and/or prevention of diseases, disorders, and conditions associated with B7-L polypeptides.

REFERENCES:
patent: 6635750 (2003-10-01), Coyle et al.
patent: 6965018 (2005-11-01), Mikesell et al.
patent: 2002/0110836 (2002-08-01), Freeman et al.
patent: 2003/0208058 (2003-11-01), Fiscella et al.
patent: 10 74 617 (2001-02-01), None
patent: WO 00/36107 (2000-06-01), None
patent: WO 00/36107 (2000-06-01), None
patent: WO 00/55375 (2000-09-01), None
patent: WO 00/61612 (2000-10-01), None
patent: WO 00/61612 (2000-10-01), None
patent: WO 01/34659 (2001-05-01), None
Attwood T., Science 2000; 290:471-473.
Skolnick et al., Trends in Biotech. 2000; 18(1)34-39.
Metzler et al., Nature Structural Biol. 1997; 4:527-531.
Burgess et al, J Cell Biol. 111:2129-2138, 1990.
Lazar et al., Mol Cell Biol. 8:1247-1252, 1988.
Bowie et al. Science, 247:1306-1310, 1990.
Henry et al., “Structure and evolution of the extended B7 family”Immunology Today, vol. 20, No. 6, Jun. 1999, pp. 285-288.
Database EMBL ′Online! Feb. 22, 2000, Isogai T et al.:Homo sapienscDNA FLJ11010 fis, clone PLACE1003145 Database accession No. AK001872, (2000).
Database EMBL ′Online! Jun. 1, 1999, Tseng et al.: “Mus musculus butyrophilin-like protein (btdc) mRNA, complete cds” retrieved from EBI Database accession No. AF142780, (1999).
Database EMBL ′Online Mar. 9, 2001, Latchman et al.: “Homo sapiensPD-1-ligand 2 protein (PDL2) m RNA, complete cds”, Database accession No. AF344424, (2001).
Database EMBL, Online “Homo sapiensbutyrophilin precursor B7-DC mRNA, complete cds”, Database Accession No. AF329193.1, (2000).
Yoshinaga et al., T-cell co-stimulation through B7RP-1 and ICOS, Nature, 402:827-32 (1999).
Ishida et al.,“Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death”, EMBO J. 11:3887-95 (1992).
Dong et al., B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion, Nat. Med. 5:1365-69 (1999).
Latchman et al., “PD-L2 is a second ligand for PD-1 and inhibits T cell activation”, 2001 Nature Immunology 2:261-68 (2001).
Nishimura et al., “Development of Lupus-like Autoimmune Diseases by Disruption of the PD-1 Gene Encoding an ITIM Motif-Carrying Immunoreceptor”, Immunity, 11:141-51 (1999).
Tseng et al., B7-DC, a New Dendritic Cell Molecule with Potent Costimulatory Properties for T Cells, J. Exp. Med. 193:839-45(2001).

Affiliated with

Also associated with

Rating

Nucleic acids encoding B7-Like molecules and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Nucleic acids encoding B7-Like molecules and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nucleic acids encoding B7-Like molecules and uses thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3996245