Chemistry: molecular biology and microbiology – Spore forming or isolating process
Patent
1993-11-04
1996-07-23
Walsh, Stephen G.
Chemistry: molecular biology and microbiology
Spore forming or isolating process
4353201, 435 691, 4352523, 43525411, 536 235, 536 2431, C12N 1512, C12N 1579, C12N 510, C12N 701
Patent
active
055388922
ABSTRACT:
Isolated DNAs (e.g., cDNAs or genomic fragments) encoding TGF-.beta. type I receptors, or soluble, ligand-binding fragments thereof; vectors or cells which contain such DNAs; and substantially pure polypeptides encoded by such DNAs, whether produced by expression of the isolated DNAs, by isolation from natural sources, or by chemical synthesis.
REFERENCES:
patent: 4404188 (1983-09-01), Donahoe et al.
patent: 4487833 (1984-12-01), Donahoe et al.
patent: 4510131 (1985-04-01), Donahoe et al.
patent: 4753794 (1988-06-01), Donahoe
patent: 4792601 (1988-12-01), Donahoe et al.
patent: 5010055 (1991-04-01), Donahoe
patent: 5011687 (1991-04-01), Donahoe et al.
patent: 5047336 (1991-09-01), Cate et al.
Hei, W. W., et al (1993) Dev. Dyn. 196: 133-42.
Attisano, L., et al. (1993) Cell 75: 671-80.
Ebner et al., Determination of Type I Receptor Specificity by the Type II Receptors of TGF.beta. or Activin, Science 262:900-901, 1993.
Franzen et al., Cloning of a TGF.beta. Type I Receptor that Forms a Heteromeric Complex with the TGF.beta. Type II Receptor, Cell 75:681-692, 1993.
Lopez-Casillas et al., Structure and Expression of the Membrane Proteoglycan Betaglycan, a Component of the TGF-.beta. Receptor System, Cell 67:785-795, 1991.
Moren et al., Molecular Cloning and Characterization of the Human and Porcine Transforming Growth Factor-.beta. Type III Receptors, Biochem. Biophys. Res. Comm. 189:356-362, 1992.
Wang et al., Expression Cloning and Characterization of the TGF-.beta. Type III Receptor, Cell 67:797-805, 1991.
Bassing et al. A Single Heteromeric Receptor Complex Is Sufficient . . . JBC 269, 14861-14864 (1994).
Bassing et al. A Transforming Growth Factor Factor .beta. Type I Receptor . . . Science 263, 87-89 (1994).
Abe et al., High concentrations of Plasma Immunoreactive Inhibin During Normal Pregnancy in Women, J. Clinical Endocrinology and Metablism 71:133-137, 1990.
Au et al., Measurement of Inhibin and an Index of Inhibiin Production by Rat Testes during Postnatal Development, Biology of Reproduction 35:37-43, 1986.
Behringer et al., Abnormal Sexual Development in Transgenic Mice Chronically Expressing Mullerian Inhibiting Substance, Nature 345:167-170, 1990.
Berta et al., Genetic Evidence Equating SRY and the Testis-determining Factor, Nature 348:48-450, 1990.
Bezard et al., Immunocytochemical Study of Anti-Mullerian Hormone in Sheep Ovarian Follicles During Fetal and Post-Natal Development, Reprod. Fert. 90:509-156, 1987.
Blanchard and Josso, Source of the Anti-mullerian Hormone Synthesized by the Fetal Testis: Mullerian-inhibiting Activity of Fetal Bovine Sertoli Cells in Tissue Culture, Pediat. Res. 8:968-971, 1974.
Boyd et al., Transforming Growth Factor-.beta. Inhibition of Epithelial Cell Proliferation Linked to the Expression of a 53-kDa Membrane Receptor, J. Biol. Chem. 264:2272, 1989.
Budzik et al., Enhanced Purification of Mullerian Inhibiting Substance by Lectin Affinity Chromatography, Cell 21:909-916, 1980.
Budzik et al., Mullerian Inhibiting Substance Fractionation by Dye Affinity Chromatography, Cell 34:307-314, 1983.
Burger et al., Serum Inhibin Concentrations Rise Througout Normal Male and Female Puberty, J. Clinical Endocrinology and Metabolism 67:689-694, 1988.
Cate et al., Development of Mullerian Inhibiting Substance as an Anti-cancer Drug, Cold Spring Harbor Symposim 51:641-647, 1986.
Cate et al., Isolation of the Bovine and Human Genes for Mullerian Inhbiting Substance and Expression of the Human Gene in Animal Cells, Cell 45:685-698, 1986.
Catlin et al., Sex-specific Fetal Lung Development and Mullerian Inhibiting Substance, Am. Rev. Respir. Dis. 141:466-470, 1990.
Catlin et al., Mullerian Inhibiting Substance Depresses Accumulation In Vitro of Disaturated Phosphatidyl-choline in Fetal Rat Lung, Am. J. Obstet. Gynecol. 159:1299-303, 1988.
Chin et al., Human Hullerian Inhibiting Substance Inhibits Tumor Growth In Vitro and In Vivo, Cancer Research, 51:201-2106, 1991.
Cohen-Haguenauer et al., Mapping of the Gene for Anti-Mullerian Hormone to the Short Arm of Human Chromosome 19, Cytogenet. Cell Genet. 44:2-6, 1987.
Coughlin et al., Mullerian Inhibiting Substance Blocks Autophosphorylation of the EGF Receptor by Inhibiting Tyrosine Kinase, Molecular and Cellular Endocrinology 49:75-86, 1987.
de Kretser et al., Serum Inhibin Levels in Normal Men and Men with Testicular Disorders, J. Endocrinology 120:517-523, 1989.
de Kretser et al., The Isolation and Physiology of Inhibin and Related Proteins, Biology of Reproduction 40:33-47, 1989.
Derynck et al., Human Transforming Growth Factor-.beta. Complementary DNA Sequence and Expression in Normal and Transformed Cells, Nature 316:701-705, 1985.
Donahoe et al., Mullerian Duct Regression in the Embryo Correlated Activity Against Human Ovarian Cancer, Science 205:913-915, 1979.
Donahoe et al., Mullerian Inhibiting Substance Inhibits Growth of a Human Ovarian Cancer in Nude Mice, Ovarian Cancer 194:472-480, 1981.
Donahoe et al., Mullerian Inhibiting Substance Activity in Bovine Fetal, Newborn and Prepubertal Testes, Biology of Reproduction 16:238-243, 1977.
Ebner et al., Cloning of a Type I TGF-.beta. Receptor and its Effect on TGF-.beta. Binding to the Type II Receptor, Science 260:1344-1348, 1993.
Epstein et al., Stainless Steel Mesh Supports High Density Cell Growth and Production of Recombinant Mullerian Inhibiting Substances, In Vitro Cellular and Developemental Biology 25:213-216, 1989.
Esch et al., Complementary Deoxyribonucleic Acid (cDNA) Cloning and DNA Sequence Analysis of Rat Ovarian Inhibins, Molecular Endocrinology 1:388-396, 1987.
Forage et al., Cloning and Sequence Analysis of cDNA Species Coding for the Two Subunits of Inhibin form Bovine Follicular Fluid, Proc. Natl. Acad. Sci. USA 83:3091-3095, 1986.
Fuller et al., Mullerian Inhibiting Substance Reduction of Colony Growth of Human Gynecologic Cancers in a Stem Cell Assay, Gynecologic Oncology 22:135-148, 1985.
Fuller et al., Mullerian Inhibiting Substance Inhibition of a Human Endomentrial Carcinoma Cell Line Xenografted in Nude Mice, Gynecologic Oncology 17:124-132, 1984.
Fuller et al., Mullerian Inhibiting Substance Inhibits Colony Growth of a Human Ovarian Carcinoma Cell Line, J. Clinical Endocrinology and Metabolism 54:1051-1055, 1982.
Georgi et al., daf-1, a C. elegans Gene Controlling Dauer Larva Development, Encodes a Novel Receptor Protein Kinase, Cell 61:635-645, 1990.
Gubbay et al., A Gene Mapping to the Sex-determining Region of the Mouse Y Chromosome is a Member of a Novel Family of Embryonically Expressed Genes, Nature 346:245-250, 1990.
Gustafson et al., Mullerian Inhibiting Substance as a Marker for Ovarian Sex-Cord Tumor, New England Journal of Medicine 326:466-471, 1992.
Hanks et al., The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains, Science 241:42-52, 1988.
Haqq et al., Isolation of the Rat Gene for Mullerian Inhibiting Substance, Geomics 12:665-669, 1992.
Hasegawa et al., Changes in Serum Concentrations of Immunoreactive Inhibin During the Oestrous Cycle of the Rat, J. Endocrinology 121:91-100, 1989.
Hsueh et al., Heterodimers and Homodimers of Inhibin Subunits have Different Paracrine Action in the . . . of Luteinizing Hormone-Stimulated Androgen Biosynthesis Proc. Natl. Acad. Sci. USA 84:5082-5086, 1987.
Hudson et al., An Immunoassay to Detect Human Mullerian Inhihbiting Substance in Males and Females During Normal Development, J. Clinical Endocrinology and Metalbolism 70:16-22, 1990.
Hutson and Donahoe, The Hormonal Control of Testicular Descent, Endocrine Reviews 7:270-283, 1986.
Josso et al., An Enzyme Linked Immunoassay for Anti-Mullerian Hormone: A New Tool for the Evaluation of Testicular Function in Infants and children, J. Clinical Endocrinology and Metabolism 70:23-27, 1990.
King et al., Mapping Anti-Mullerian Hormone (Amh) and Related Sequences in the Mouse: Identification of a New Region of Homology Between MMU10 and HSA19p, Genomics 11:273-283, 1991.
Knebelmann et al., Anti-Mullerian Hormone Bruxelles: A Nonsense Mutuation Associated with the Persistent Mullerian Duct Synd
Donahoe Patricia K.
Gustafson Michael
He Wei-Wu
Wang Xiao-Fan
Duke University
Fitzgerald David L.
The General Hospital Corporation
Walsh Stephen G.
LandOfFree
Nucleic acids encoding a TGF-.beta. type 1 receptor does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Nucleic acids encoding a TGF-.beta. type 1 receptor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nucleic acids encoding a TGF-.beta. type 1 receptor will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-712434