Nucleic acids encoding a house dust mite allergen, Der p...

Details Nucleic acids encoding a house dust mite allergen, Der p... Nucleic acids encoding a house dust mite allergen, Der p...

2005-02-01

2005-02-01

Duffy, Patricia A. (Department: 1645)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S070100, C435S071100, C435S071200, C435S252300, C435S320100, C435S325000, C536S023500

Reexamination Certificate

active

06849427

ABSTRACT:
A novel protein allergen Der p VII ofDermatophagoides pteronyssinusis described. A cDNA clone encoding Der p VII was isolated from a λgt11 library ofD. pteronyssinuscDNA. The nucleic acid sequence of Der p VII encodes a 198 residue mature processed protein having a predicted molecular weight of 22,177 daltons. Der p VII protein may be used as the active ingredient in therapeutic composition for the treatment of sensitivity to house dust mites. The protein may also be used in methods of diagnosing such sensitivity.

REFERENCES:
patent: 4745051 (1988-05-01), Smith et al.
patent: 5077214 (1991-12-01), Guarino et al.
patent: 5427925 (1995-06-01), Gearing et al.
patent: 0 473 111 (1992-03-01), None
Stewart et al, AJEBAK 58(Pt 3):259-74 (1980).*
Stewart et al. Int. Archs Allergy Appl. Immunol. 69:224-230 (1982).*
Abe et al. Allergy 42:352-58 1987.*
Chua et al. Int. Archs. Allergy Appl. Immunol. 91: 118-123 (1990).*
Bowie et al. Science 247: 1306-1310 Mar. 1990.*
Lazar et al., Mol. Cell Biology 8(3):1247-1252, 1988.*
Burgess et al., J. Cell Biology 111:2129-37, 1990.*
Shen, H. et al., “Molecular cloning of a house dust mite allergen with common antibody binding specificities with multiple components in mite extracts”,Clinical and Experimental Allergy, vol. 23, pp. 934-940 (1993).
Tovey, Euan, R. et al, (1989) “The Cloning of a Mite (Dermatophagoides Pteronyssinus) Recombinant Protein that shares IgE—binding Determinants with a 14-15 KD Component of Mite Extracts”, Advances in Biosciences, vol. 74, pp. 33-43.
Yuuki Toshifumi et al, (1991) “Cloning and Expression of cDNA Coding for the Major House Dust Mite Allergen Derf II inEscherichia coli” vol. 55(5), pp. 1233-1238.
Bengtsson et al., “Detection of Allergens in Mould and Mite Preparations by a Nitrocellulose Electroblotting Technique” Int. Arch. Allergy Appl. Immun. 1986, vol. 80, pp. 383-390.
Chapman et al., “Purification and Characterization of the Major Allergen from Dermatophagoides Pteronyssinus-Antigen P1.” Journal of Immunology 1980, vol. 125, No. 2, 587-592.
Chua et al., “Expression ofDermatophagoides pteronyssinusAllergen, Der pII, inEscherichia coliand the Binding Studies with Human IgE” Int. Arch. Allergy Appl. Immunol. 1990, vol. 91, pp. 124-129.
Ford et al., “The spectrum of low molecular weight house dust mite (Dermatophagoides pteronyssinus) allergens with emphasis on Der p II” Clinical and Experimental Allergy 1990, vol. 20, No. 1, pp. 27-31.
Greene et al., “IgE Binding Structures of the Major House Dust Mite Allergen DER P I” Molecular Immunology 1992, vol. 29, No. 2, pp. 257-262.
Greene et al., “Antigenic Analysis of Group I House Dust Mite Allergens Using Random Fragments of Der p I Expressed by Recombinant DNA Libraries” Int. Arch. Appl. Allergy Immunol. 1990, vol. 92, pp. 30-38.
King et al., “Chemical and Biological Properties of Some Atopic Allergens” Advances in Immunology 1976, vol. 23, pp. 77-105.
Kohmoto et al., “Activation of the Kallikrein-Kinin System in Human Plasma by a Scrine Protease from Mites” Journal Clin. Biochem. Nutr. 1991, vol. 10, pp. 15-20.
Lind “Purification and partial characterization of two major allergens from the house dust miteDermatophagoides pteronyssinus” Journal of Allergy and Clinical Immunology 1985, vol. 76, No. 5, pp. 753-761.
Lind et al., “Identification of Allergens inDermatophagoides pteronyssinusMite Body Extract by Crossed Radioimmunoelectrophoresis with Two Different Rabbit Antibody Pools” Scand. J. Immunol. 1983, vol. 17, pp. 263-273.
Stewart et al., “The group III allergen from the house dust miteDermatophagoides pteronyssinusis a trypsin-like enzyme” Immunology 1992, vol. 75, pp. 29-35.
Stewart et al., “Standardization of Rye-Glass Pollen (Lolium perenne) Extract” Int. Arch. Allergy Appl. Immun. 1988, vol. 86, pp. 9-18.
Thomas et al. “Cloning and Expression of DNA Coding for the Major House Dust Mite Allergen Der p I inEscherichia coli” Int. Arch. Allergy Appl. Immun. 1988, vol. 85, pp. 127-129.
Tovey et al., “Comparison by electroblotting of IgE-binding components in extracts of house dust mite bodies and spent mite culture” Journal of Allergy and Clinical Immunology 1987, vol. 79, No. 1, pp. 93-102.
Van der Zee et al., “Skin tests and histamine release with P1-depletedDermatophagoides pteryssinusbody extracts and purified P1” Journal of Allergy and Clinical Immunology 1988, vol. 81, No. 5, pp. 884-896.
Baldo et al. “Toward a Definition of the ‘Complete’ Spectrum and Rank Order of Importance of the Allergens from the House Dust Mite:Dermatophagoides pteronyssinus” Adv. Bioscience 1989, 74:13-31.

Affiliated with

Also associated with

Rating

Nucleic acids encoding a house dust mite allergen, Der p... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Nucleic acids encoding a house dust mite allergen, Der p..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nucleic acids encoding a house dust mite allergen, Der p... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3450314