Nucleic acid structures with catalytic and autocatalytic replica

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 91, 536 231, 536 243, C12Q 168, C12P 1934, C12N 1511

Patent

active

054728401

ABSTRACT:
Methods and compositions are described for making ribozymes which can release or activate molecules including autocatalytically replicatable RNA such as MDV-1.

REFERENCES:
patent: 4957858 (1990-09-01), Chu et al.
Uhlenbeck (1987), Nature 328: 596-600.
Forster et al. (1987), Cell 50: 9-16.
Syvanen et al. (1986), Nucl. Acids Res. 14(12):5037-5048.

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