Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-06-07
1997-10-28
Wax, Robert A.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 693, 536 237, C12P 2102, C07H 2104
Patent
active
056817169
ABSTRACT:
Nucleic sequences from the genome of Salmonella Typhi include all or part of the genetic information required for the in vitro infection of cultured HeLa cells by Salmonella bacteria. Polypeptides encoded by these nucleic sequences are also described, as is the use of said polypeptides and nucleic sequences for implementing methods of in vitro Salmonella detection in biological samples which are thought to contain it.
REFERENCES:
Galan, J.E. et al. (1990) "Expression of Salmonella typhimurium genes required for invasion is regulated by changes in DNA supercoiling" Infect. & Immun. 58(6):1879-1885.
Elsinghorst, E.A. et al. (1989) "Penetration of human intestinal epithelial cells by Salmonella: molecular cloning and expression of Salmonella typhi invasion determinants in Escherichai coli" Proc. Nat'l. Acad. Sci., USA 86:5173-5177.
Dion Michel
Popoff Michel Yvan
Institut National de la Sante et de la Recherche Medicale
Institut Pasteur
Lau Kawai
Wax Robert A.
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