Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase
Reexamination Certificate
2006-08-29
2006-08-29
Prouty, Rebecca E. (Department: 1652)
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Oxidoreductase
C435S190000, C435S025000, C435S419000, C435S415000, C435S412000, C435S252300, C435S254200, C435S320100, C435S069100, C435S325000, C435S410000, C536S023200, C536S023600, C530S350000
Reexamination Certificate
active
07098011
ABSTRACT:
This invention relates to an isolated nucleic acid sequence encoding isoflavone synthase. The invention also relates to the construction of chimeric sequences encoding all or a substantial portion of the enzymes, in sense or antisense orientation, wherein expression of the chimeric sequence results in production of altered levels of the enzyme in a transformed host cell.
REFERENCES:
patent: 5846784 (1998-12-01), Hitz
patent: 776161 (2000-09-01), None
patent: WO 99/19493 (1999-04-01), None
patent: WO 00/46356 (2000-08-01), None
patent: WO 00/53771 (2000-09-01), None
Bork , Genome Research, 10:398-400, 2000.
Broun et al. , Science 282:1315-1317, 1998.
Seffernick et al. , J. Bacteriol. 183(8):2405-2410, 2001.
Van de Loo et al. , Proc. Natl. Acad. Sci. 92:6743-6747, 1995.
Witkowski et al. , Biochemistry 38:11643-11650, 1999.
EMBL Sequence Library Data Accession No. : AF022462, Jan. 8, 1998, B. Siminsky et al., Expression of a Soybean Cytochrome P450 Monooxygenase cDNA tobacco enhances the metabolism of phenylurea herbicides.
C. R. Schopfer et al., Mol. Gen. Genet., vol. 258:315-322, 1998, Identification of elicitor-induced cytochrome P450s of soybean (Glycine maxL.) using differential display of mRNA.
Tomoyoshi Akashi et al., Plant Science, vol. 126:39-47, 1997, Cloning of cytochrome P450 cDNAs from culturedGlycymhiza echinataL. cells and their transcriptional activation by elicitor-treatment.
Takashi Hakamatsuka et al., Chem. Pharm. Bull., vol. 37(1):249-252, 1989, Isoflavone synthase from cell suspension cultures of Pueraria Lobata.
S. P. Colliver et al., Plant Mol. Biol., vol. 35:509-522, 1997 , Differential modification of flavonoid and isoflavonoid biosynthesis with an antisense chalcone synthase construct in transgenicLotus comiculatus.
Christopher L. Steele et al., Arch. of Biochem. & Biophys., vol. 367(1):146-150, 1999, Molecular characterization of the enzyme catalyzing the aryl migration reaction of Isoflavonoid Biosynthesis in Soybean.
Tomoyoshi Akashi et al., Plant Phys., vol. 121:821-828, 1999, Cloning and functional expression of a cytochrome P450 cDNA encoding 2-Hydroxyisoflavone Synthase involved in biosynthesis of the isoflavonoid skeleton in licorice.
Donald A. Phillips, Phenolic Metabolism in Plants, edited y H. A. Stafford et al., 1992, pp. 201-231, Flavonoids: Plant signals to soil microbes.
Michael Naim et al., J. Agric. Food Chem., vol. 24(6):1174-1177, 1976, Antioxidative and Antihemolytic activities of soybean isoflavones.
Michael Naim et al., J. Agric. Food Chem., vol. 22(5):806-810, 1974, Soybean isoflavones, characterization, determination, and antifungal activity.
K. R. Price et al., Food Add & Cont., vol. 2(2):73-106, 1985, Naturally occurring oestrogens in foods—A review.
Mark Messina et al., J. Natl. Cancer Inst., vol. 83(8):541-545, The role of soy products in reducing risk of cancer.
Greg Peterson et al., Biochem. and Biophys. Res. Comm., vol. 179(1):661-667 , 1991 , Genistein inhibition of the growth of human breast cancer cells: Independence from estrogen receptors and the multi-drug resistance gene.
K. S. Mathur et la., J. Nutrition, vol. 84:201-204, 1964, Effect of bengal gram on experimentally induced high levels of cholesterol in tissues and serum in albino rats.
R. D. Sharma, Lipids, vol. 14(6):535-540, Isoflavones and hypercholesterolemia in rats.
Chigen Tsukamoto et al., J. Agric. Food Chem., vol. 43:1184-1192, 1995, Factors affecting isoflavone content in soybean seeds: Changes in isoflavones, saponins, and Composition of fatty acids at different temperatures during seed development.
Huei-Ju Wang et al., J. Agric. Food Chem., vol. 42:1674-1677, 1994, Isoflavone composition of American and Japanese soybeans in Iowa: Effects of variety, crop year, and location.
Richard A. Dixon et al., Plant Cell, vol. 7:1085-1097, 1995, Stress-Induced Phenylpropanoid Metabolism.
J. Rowell M. Potts et al., J. of Biol. Chem., vol. 249(16):5019-5026, 1974, The 4-Hydroxylation of cinnamic acid by Sorghum Microsomes and the requirement for cytochrome P450.
Tomoyoshi Akashi et al., Biochem & Biophys. Res. Comm., vol. 251:67-70, 1998, CYP81E1, a cytochrome P450 cDNA of licorice (Glycrmhiza echinataL. ) , encodes Isoflavone 2′-Hydroxylase.
Christel R. Schopfer et al., FEBS Lett., vol. 432:182-186, 1998, Molecular characterization and functional expression of dihydroxypterocarpan 6a-hydroxylase, an enzyme specific for pterocarpanoid phytoalexin biosynthesis in soybean (Glycine max.L.).
M. Hagmann et al., FEBS, vol. 175(2):199-202, 1984, Enzymatic rearrangement of flavonone to isoflavone.
Georg Kochs et al., Eur. J. Biochem., vol. 155:311-318, 1986, Enzymic synthesis of isoflavones.
Clint Chapple, Annu. Rev. Plant Physiol. Plant Mol. Biol., vol. 49:311-343, 1998, Molecular-Genetic analysis of plant cytochrome P450-dependent monooxygenases.
Erich Grotewold et al., Plant Cell, vol. 10:721-740, 1998, Engineering secondary meatbolism in maize cells by ectopic expression on transcription factors..
Robert W. M. Sablowski et al., Embo J., vol. 13(1):128-137, 1994, A flower-specific Myb protein activates transcription of phenylpropanoid biosynthetic genes.
Mark D. Adams et al., Science, vol. 252:1651-1656, 1991, Complementary DNA Sequencing: Expressed sequence tags and human genome project.
Stephen F. Altschul et al., J. Mol. Biol., vol. 215:403-410, 1990, Basic Local Alignment Search Tool.
Warren Gish et al., Nature genetics, vol. 3:266-272, 1993, Identification of protein coding regions by database similarity search.
National Center for Biotechnology Information General Identifier No. 2739005, Mar. 2, 1999, B. Siminszky et al., Expression of a soybean cytochrome P450 monooxygenase cDNA in yeast and tobacco enhances the metabolism of phenhylurea herbicides.
Balazs Siminszky et al., PNAS, vol. 96:1750-1755, 1999, Expression of a soybean cytochrome P450 monooxygenase cDNA in yeast and tobacco enhances the metabolism of phenhylurea herbicides.
Muhammed Faisal Hashim et al., FEBS Lett., vol. 271(1,2):219-222, 1990, Reaction mechanism of oxidative rearrangement of flavanone in isoflavone biosynthesis.
National Center for Biotechnology Information General Identification No. 1359894, Oct. 7, 1996, M. Hasenfratz et al., Multiple forms of NADPH-cytochrome P450 reductase in higher plants.
Denis Pompon et al., Methods in Enzymol., vol. 272:51-64, 1996, Yeast expression of animal and plant P450s in Optimized redox environments.
National Center for Biotechnology Information General Identifier No. 984798, Sep. 14, 1995, R. S. Sikorski et al., A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA inSaccharomyces cerevisiale.
Robert S. Sikorski et al., Genetics, vol. 122:19-27, 1989, A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA inSaccharomyces cerevisiaie.
Shao-Bing Hua et al., Plasmid, vol. 38:91-96, 1997, Minimum length of sequence homology required for in vivo cloning by homologous recombination in yeast.
J. Geigert et al., Tetrahedron, vol. 29:2703-2706, 1973, Two phytoalexins from sugarbeet (beta vulgaris) leaves.
Desmond G. Higgins et al., Cabios Comm, vol. 5(2):151-153, 1989, Fast and sensitive multiple sequence alignments on a microcomputer.
Mark H. Harpster et al., Mol. Gen. Genet., vol. 212:182-190, 1988, Relative strengths of the 35S califlower mosaic virus, 1′, 2′, and nopaline synthase promoters in transformed tobacco sugarbeet and oilseed rape callus tissue.
A. Depicker et al., J. Mol. & Appl. Genet., vol. 1(6):561-573, 1982, Nopaline synthase: Transcript mapping and DNA sequence.
Peter Hajdukiewicz et al., Plant Mol. Biol., vol. 25:989-994, 1994, The small, versatile pPZP family of Agrobacterium binary vectors for plant transformation.
R. Deblaere et al., Methods in Enzymol., vol. 153:277-292, 1987, Vectors for Cloning in Plant Cells.
Pauline A. Bariola et al., Plant Phys., vol. 119:331-342, 1999, Regulation of S-like ribonuclease levels in arabidopsis. Antisense inhibition of RNS1 or RNS2 elevates Anthocyanin accumulation.
G. Murray Bal
Fader Gary M.
Jung Woosuk
McGonigle Brian
Odell Joan T.
Yu Xiaodan
E. I. du Pont de Nemours and Company
Prouty Rebecca E.
Ramirez Delia M.
LandOfFree
Nucleic acid sequences encoding isoflavone synthase does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Nucleic acid sequences encoding isoflavone synthase, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nucleic acid sequences encoding isoflavone synthase will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3606909