Nucleic acid sequence of senescence asssociated gene

Details Nucleic acid sequence of senescence asssociated gene Nucleic acid sequence of senescence asssociated gene

1997-11-19

2000-02-15

Huff, Sheela

Chemistry: molecular biology and microbiology

Vector, per se

536 231, 536 235, 536 241, 4353201, 435325, C07H 2104, C12N 1563, C12N 1585, C12N 1511

Patent

active

060251948

ABSTRACT:
Human gene GC6 is expressed more abundantly in senescent cells than young cells. Isolated, purified, and recombinant nucleic acids and proteins corresponding to the human GC6 gene and its mRNA and protein products, as well as peptides and antibodies corresponding to the GC6 protein can be used to identify senescent cells, distinguish between senescent and young cells, identify agents that alter senescent gene expression generally and GC6 expression specifically; such agents as well as GC6 gene and gene products and products corresponding thereto can be used to prevent and treat diseases and conditions relating to cell senescence.

REFERENCES:
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