Nucleic acid sequence encoding ovarian antigen, CA125, and...

Details Nucleic acid sequence encoding ovarian antigen, CA125, and... Nucleic acid sequence encoding ovarian antigen, CA125, and...

2007-04-17

2007-04-17

Ungar, Susan (Department: 1642)

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

C435S325000, C435S069100, C435S320100, C536S023100, C536S023500

Reexamination Certificate

active

10243243

ABSTRACT:
The present invention provides an isolated nucleic acid molecule comprising sequences encoding the CA125 protein or a portion thereof. This invention also provides a method to detect ovarian cancer in a subject. Furthermore, this invention provides a method for the diagnosis of a cancer which expresses CA125 by detecting CA125-expressing cells in the blood or other fluids of patients. This invention also provides a method of producing CA125 protein. This invention also provides a method of silencing CA125 protein production. Finally, this invention provides a method to treat or prevent cancer using a vaccine comprising CA125 nucleic acid or protein.

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