Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1993-11-17
1996-12-17
Zitomer, Stephanie W.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
435 6, 435 911, 435 912, 435803, 210656, 436161, 536 231, 536 253, 5263472, 935 76, 935 77, 935111, C12Q 170, C08F11208, C12N 1500, B01D 1508
Patent
active
055852360
ABSTRACT:
Nonporous polymer beads having an average diameter of about 1-100 microns are suitable for chromatographic separation of mixtures of nucleic acids when the polymer beads are alkylated with alkyl chains having at least three carbon atoms. The polymer beads provide efficient separation of nucleic acids using ion-pair reverse phase chromatography.
REFERENCES:
patent: 4563510 (1986-01-01), Ugelstad
Journal Of Chromatography, (1990), 508:61-73, "Rapid High-Performance Liquid Chromatography of Nucleic Acids With Polystyrene-Based Micropellicular Anion Exchangers", MAA et al.
Nucleic Acids Research, (1993), 21:1061-1066, High-Resolution Liquid Chromatography Of DNA Fragments On Non-Porous Poly(Styrene-Divinylbenzene) Particles , Huber et al.
Journal Of Cromatography, (1992), 599:113-118, "High-Performance Liquid Chromatographic Separation Of Detritylated Oligonuceotides On Highly Cross-Linked Poly(Styrene-Divinylbenzene) Particles", Huber.
Journal Of Chromatography, (1986), 359:265-274, "Separation Of DNA Restriction Fragments By Ion-Pair Chromatography", Eriksson et al.
Analytical Biochemistry, (1985), 151:526-533, "Isolation Of Specific tRNAs Using An Ionic-Hydrophobic Mixed-Mode Chromatographic Matrix", Bischoff et al.
Bonn Gunther
Huber Christian
Oefner Peter
Sarasep, Inc.
Sisson Bradley L.
Walker William B.
Zitomer Stephanie W.
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