Nucleic acid respiratory syncytial virus vaccines

Details Nucleic acid respiratory syncytial virus vaccines Nucleic acid respiratory syncytial virus vaccines

1995-06-07

2000-02-01

Guzo, David

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

4353201, 514 44, C12N 1563, A61K 3170

Patent

active

060199806

ABSTRACT:
Vectors containing a nucleotide sequence coding for an F protein of respiratory syncytial virus (RSV) and a promoter for such sequence, preferably a cytomegalovirus promoter, are described. Such vectors also may contain a further nucleotide sequence located adjacent to the RSV F protein encoding sequence to enhance the immunoprotective ability of the RSV F protein when expressed in vivo. Such vectors may be used to immunize a host, including a human host, by administration thereto. Such vectors also may be used to produce antibodies for detection of RSV infection in a sample.

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