Chemistry: molecular biology and microbiology – Process of utilizing an enzyme or micro-organism to destroy... – Treating animal or plant material or micro-organism
Reexamination Certificate
2011-06-28
2011-06-28
Sisson, Bradley L (Department: 1634)
Chemistry: molecular biology and microbiology
Process of utilizing an enzyme or micro-organism to destroy...
Treating animal or plant material or micro-organism
C435S006120, C435S091200, C435S219000, C436S094000, C536S023100
Reexamination Certificate
active
07968327
ABSTRACT:
This invention provides methods of quantitating nucleic acids from problematic samples, such as aged samples, formalin fixed samples, paraffin embedded samples, samples with aneuploid cells, and cells with fragmented nucleic acids. Methods include techniques to efficiently solublize the nucleic acids under non-denaturing conditions from preserved clinical samples without resort to organic extractions, to normalize cell counts regardless of aneuploidy, to access the fragmentation state of the nucleic acids, and to provide standard curves for degraded nucleic acid samples.
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Davies Joan
Luo Yuling
Ma Yunqing
McMaster Gary
Baker Gary
Quine Intellectual Property Law Group P.C.
Sisson Bradley L
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