Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1988-09-30
1992-06-02
Moskowitz, Margaret
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 26, 536 28, 536 29, 435 6, 935 77, 935 78, 436501, 436 94, C07H 1512, C12Q 168, G01N 33566, G01N 3348
Patent
active
051188015
ABSTRACT:
A probe for the detection of a nucleic acid target sequence containing a molecular switch comprising three essential elements: a probe sequence of 20-60 nucleotides surrounded by switch sequences of 10-40 nucleotides which are complementary to each other, wherein the state of the switch is useful for selectively generating a detectable signal if the probe is hybridized to a target; also, assays and kits utilizing such probes.
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Buyoli Hilda M. L.
Guerra Cesar E.
Kramer Fred R.
Lizardi Paul M.
Tyagi Sanjay
Moskowitz Margaret
The Public Health Research Institute
The Salk Instiute for Biological Studies
Zitomer Stephanie W.
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