Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1993-12-14
1996-11-05
Jones, W. Gary
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435810, 436501, 536 221, 536 231, 536 241, 536 243, 536 2431, 536 2432, 536 2433, 935 77, 935 78, C12Q 168, C07H 2104
Patent
active
055716709
ABSTRACT:
Linear or branched oligonucleotide multimers useful as amplifiers in biochemical assays which comprise (1) at least one first single-stranded oligonucleotide unit that is complementary to a single-stranded oligonucleotide sequence of interest, and (2) a multiplicity of second single-stranded oligonucleotide units that are complementary to a single-stranded labeled oligonucleotide. Amplified sandwich nucleic acid hybridizations and immunoassays using the multimers are exemplified.
REFERENCES:
patent: 4299916 (1981-11-01), Litman et al.
patent: 4563419 (1986-01-01), Ranki et al.
patent: 4749647 (1988-06-01), Thomas et al.
patent: 4828979 (1989-05-01), Klevan et al.
patent: 4882269 (1989-11-01), Schneider et al.
patent: 4910300 (1990-03-01), Ursdea et al.
patent: 4925785 (1990-05-01), Wang et al.
patent: 5175270 (1992-12-01), Nilsen et al.
Palmer et al. (1986) Plasmid, vol. 16, pp. 52-62.
Chu et al., Nucleic Acids Research (1986) 14(14):5591-5603.
Synanen et al., Nucleic Acids Research (1986) 14(12):5037-5048.
Syvanen et al., Nucleic Acids Research (1988) 16(23):11327-11338.
Fahrlander et al., "Amplifying DNA probe signals: a `Christmas tree` approach" Bio/Technology (1988) 6:1165-1168.
Ziemer et al., "Sequence of Hepatitis B virus DNA incorporated into the genome of human hepatoma cell line" Virology (1985) 53:(3):885-892.
Clyne Jennifer M.
Urdea Michael S.
Blackburn Robert P.
Chiron Corporation
Goldman Kenneth M.
Jones W. Gary
Marschel Ardin H.
LandOfFree
Nucleic acid probes useful in detecting Chlamydia trachomatis an does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Nucleic acid probes useful in detecting Chlamydia trachomatis an, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nucleic acid probes useful in detecting Chlamydia trachomatis an will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2014208