Nucleic acid probes to Coccidioides immitis

Details Nucleic acid probes to Coccidioides immitis Nucleic acid probes to Coccidioides immitis

1991-12-18

1994-02-08

Parr, Margaret

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

536 243, 536 2433, C12Q 168, C07H 2104

Patent

active

052847470

ABSTRACT:
A nucleotide polymer probe having the nucleotide sequence of SEQ ID NO. 1 or SEQ ID NO. 6 able to hybridize at 60.degree. C. in 0.1M lithium succinate buffer containing 10% lithium lauryl sulfate to rRNA or rDNA from Coccidioides immitis and not to rRNA or rDNA from Auxarthron thaxteri, Blastomyces dermatitidis, Geotrichum candidum, Gymnoascus dugwayensis, Histoplasma capsulatum, and Malbranchea albolutea. A method to distinguish Coccidioides immitis from Auxarthron thaxteri, Blastomyces dermatitidis, Geotrichum candidum, Gymnoascus dugwayensis, Histoplasma capsulatum, and Malbranchea albolutea using said probe is also disclosed.

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