Nucleic acid probes for the detection of bacteria of the genus L

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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536 243, 536 2432, 536 2433, C12Q 168, C07H 2104

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active

055695868

ABSTRACT:
Nucleic acid sequences which hybridize preferentially to the 16S or 23S rRNA or rDNA of Legionella sp., L. pneumophila, L. micdadei, a L. pneumophila, or a Legionella subset are taught. These organisms are the etiological agents of Legionnaires' disease, Pontiac fever, Pittsburgh pneumonia and other infections. The nucleic acids are useful in the detection of these pathogenic microorganisms. Probes based on these sequences and kits containing the probes are also disclosed.

REFERENCES:
patent: 4851330 (1989-07-01), Kohne
Fox et al., Syst. Appl. Microbiol. 11, 135-139 (1989).
Fox et al., Syst. Appl. Microbiol 14, 52-56 (1991).
FEMS Microbiol. Lett., B ottger, vol. 65, 171-176 (1989).
Am. J. Clin. Path., Fain et al., vol. 95(5), 719-724 (1991).

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