Nucleic acid probes for prenatal sexing

Details Nucleic acid probes for prenatal sexing Nucleic acid probes for prenatal sexing

1986-06-05

1990-10-02

Warden, Robert J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

4351723, 436501, 436814, 536 27, 935 3, 935 9, 935 63, 935 78, C12Q 168, C07H 1512

Patent

active

049606905

ABSTRACT:
Nucleic acid hybridizaiton probes are provided which have sequences complementary to sequences of segments in bovine male-specific DNA and are suitable for sexing bovine embryos at the time of embryo transfer with nearly 100% accuracy.

REFERENCES:
Nallaseth, F. S. et al., "Isolation of Recombinant . . . Male-Specific Mo DNA", Mol. Gen. Genet 190, 80-84 (1983).
Gosden, J. R. et al., "Rapid Fetal Sex Determination . . ." The Lancet 1, 540-541, Mar. 10, 1984.
Burns, J. et al., "Sensitive System for Visualizing . . ." J. Clin. Pathol 38, 1085-1092 (1985).
Bishop et al., "Single Copy DNA Sequences Specific for the Human Y Chromosome", Nature 303, 831-832 (1983).
Kunkel et al., "Organization and Heterogeneity of Sequences", Biochemistry 18, 3343-3353 (1979).
Langer, P. R. et al., "Enzymatic Synthesis of Biotive-Labeled Polynucleatides . . .", Proc. Natl. Acad. Sci. U.S.A. 78(11), 6633-6637 (Nov., 1981).
Lamar et al., "Y-encoded Species-Specific DNA in Mice . . .", Cell 37, 171-177 (1984).

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