Nucleic acid probes and methods

Details Nucleic acid probes and methods Nucleic acid probes and methods

1996-09-06

1998-01-13

Campbell, Eggerton A.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 912, C12Q 168, C12P 1934

Patent

active

057078130

ABSTRACT:
The present invention is directed to compositions comprising an oligonucleotide linked to a detectably labeled marker component comprising a fluorophore moiety which comprises a substantially planar, multidentate macrocyclic ligand coordinated to a central atom capable of coordinating with two axial ligands and two polyoxyhydrocarbyl moieties which are attached as axial ligands to the central atom. The present invention is also directed to nucleic acid hybridization and amplification methods employing such compositions.

REFERENCES:
patent: 5403928 (1995-04-01), Dandliker et al.
patent: 5606045 (1997-02-01), Dandliker et al.

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