Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1994-05-17
1996-01-23
Zitomer, Stephanie W.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
536 2432, C12Q 168, C07H 2104
Patent
active
054864542
ABSTRACT:
Nucleic acid probes that detect Salmonella human pathogens are generated from the nucleotide sequences of a gene encoding a virulence factor involved in the pathogenesis of Salmonella, especially the Type 1 fimbriae protein. Preferred probe lengths are about 20 to about 100 nucleotide bases. The probes are highly specific and sensitive for detecting Salmonella organisms pathogenic to humans and are thus clinically useful in the detection of infection in diarrhea specimens. They also may be used in the detection of food-borne Salmonella, the causative agent of most salmonellosis in humans.
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Madonna M. Jane
Woods Derek
Ortho Diagnostic Systems Inc.
Zitomer Stephanie W.
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