Nucleic acid primers for detecting micrometastasis of prostate c

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 911, 435 912, 435810, 536 231, 536 2431, 536 2433, 536 245, C07H 2102, C07H 2104, C12P 1934, C12Q 168

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056746822

ABSTRACT:
Oligonucleotides for and a method of diagnosing prostate micrometastasis are provided by the present invention whereby nucleic acids from a tissue sample from a patient are isolated, nucleic acids from the tissue sample specific for prostate cancer are amplified, or a signal generated by hybridization of a probe specific to a prostate cancer specific nucleic acid is amplified; and detection of amplified nucleic acids is indicative of micrometastasis of prostate cancer.

REFERENCES:
Lundwall, Bioch. Biophy. Res. Comm. 161(3): 1151-1159, 1989.
Schulz, Nuc. Acids Res. 16(13): 6226, 1988.
O'Garra, A. and Vieira, P., "Polymerase chain reaction for detection of cytokine gene expression", Current Opinion in Immunology, 1992, 4:211-215.

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