Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1994-12-15
1997-10-07
Zitomer, Stephanie W.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 911, 435 912, 435810, 536 231, 536 2431, 536 2433, 536 245, C07H 2102, C07H 2104, C12P 1934, C12Q 168
Patent
active
056746822
ABSTRACT:
Oligonucleotides for and a method of diagnosing prostate micrometastasis are provided by the present invention whereby nucleic acids from a tissue sample from a patient are isolated, nucleic acids from the tissue sample specific for prostate cancer are amplified, or a signal generated by hybridization of a probe specific to a prostate cancer specific nucleic acid is amplified; and detection of amplified nucleic acids is indicative of micrometastasis of prostate cancer.
REFERENCES:
Lundwall, Bioch. Biophy. Res. Comm. 161(3): 1151-1159, 1989.
Schulz, Nuc. Acids Res. 16(13): 6226, 1988.
O'Garra, A. and Vieira, P., "Polymerase chain reaction for detection of cytokine gene expression", Current Opinion in Immunology, 1992, 4:211-215.
Croce Carlo
Fischer Rainer
Gomella Leonard
Moreno Jose G.
Mulholland S. Grant
Thomas Jefferson University
Tran Paul B.
Zitomer Stephanie W.
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