Nucleic acid molecules encoding SIGIRR polypeptides

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Reexamination Certificate

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C435S071100, C435S320100, C435S471000, C435S325000, C435S252300, C435S255100, C435S252100, C435S419000, C536S023500, C530S350000, C436S504000

Reexamination Certificate

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07037675

ABSTRACT:
The invention is directed to purified and isolated SIGIRR polypeptides and fragments thereof, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides derived from these polypeptides, and uses thereof.

REFERENCES:
Thomassen et al. Identification and Characterization of SIGIRR, a molecule representing a novel subtype of the IL-R1 superfamily. Cytokine, vol. 11, No. 6, 1999, pp. 389-399.
Nucleotide Sequence Database EMBL ID Accession No. AA490809, Jul. 3, 1997, Strawberg et al.
Dower et al., Biomembranes, 6:147-175 (1996).
GenBank Accession No. R88163, Aug. 16, 1995, Hillier et al.
Deng, et al., “Loss of Heterozygosity in Normal Tissue Adjacent to Breast Carcinomas”, Science, 274: 2057-2059 (1996).
Mantovani et al., J. Leukoc. Biol., 75(5):738-742 (2004)—(Abstract Only).
O'Neill, Nature Immunol., 4(9):823-824 (2003).
Polentarutti et al., Eur. Cytokine Netw., 14(4):211-218 (2003)—(Abstract Only).
Wald et al., Nature Immunol., 4(9):920-927 (2003).

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