Nucleic acid molecules encoding human tumor necrosis factor...

Details Nucleic acid molecules encoding human tumor necrosis factor... Nucleic acid molecules encoding human tumor necrosis factor...

2006-09-19

2006-09-19

Gambel, Phillip (Department: 1644)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S252330, C435S326000, C530S387100, C536S023500

Reexamination Certificate

active

07109320

ABSTRACT:
An antibody variable region of a monoclonal antibody specifically binding to human tumor necrosis factor-α contains at least one of a heavy chain variable region and a light chain variable region having specific complementarity determining regions therein. A nucleic acid molecule encoding the same, a recombinant vector containing the nucleic acid molecule, and a cell transformed with the recombinant vector are also provided.

REFERENCES:
Janeway et al, Immunobiology, p. 3.2, Garland Publishing, New York, 1997.
Rudikoff et al., Proc. Natl. Acad. Sci. 79: 1979-1983 (1982).
C. Chothia et al., “Conformations of immunoglobulin hypervariable regions”,Nature, vol. 342, Dec. 21-28, 1989, pp. 877-883.
E. Döring et al., “Identification and Characterization of a TNFα Antagonist Derived from a Monoclonal Antibody”,Molecular Immunology, vol. 31, No. 14, 1994, pp. 1059-1067.

Affiliated with

Also associated with

Rating

Nucleic acid molecules encoding human tumor necrosis factor... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Nucleic acid molecules encoding human tumor necrosis factor..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nucleic acid molecules encoding human tumor necrosis factor... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3604929