Nucleic acid molecules encoding glutx and uses thereof

Details Nucleic acid molecules encoding glutx and uses thereof Nucleic acid molecules encoding glutx and uses thereof

1998-02-26

1999-08-24

Degen, Nancy

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 691, 435440, 435455, 435471, 4353201, 435325, 435243, 536 231, 536 234, 536 235, 536 243, 536 2431, 530350, C12Q 168, C12N 1500, C07H 2104, C07H 2102

Patent

active

059423986

ABSTRACT:
The invention concerns the human gene encoding GLUTX, a glucose transporter. GLUTX nucleic acid and polypeptides, as well as molecules which increase or decrease expression or activity of GLUTX, are useful in the diagnosis and treatment of disorders associated with aberrant hexose transport.

REFERENCES:
Databases embl and genbank on MPSRCH, accession No. F00548, Sep. 21, 1995.
Fukumoto et al., "Cloning and Characterization of the Major Insulin-responsive Glucose Transporter . . . " J. of Biol. Chem. 264:7776-7779, 1989.
Kayano et al., "Human Facilitative Glucose Transporters" J. of Biol. Chem. 265:13276-13282, 1990.
Keller et al., "Functional Expression of the Human HepG2 and Rat Adipocyute Glucose . . . " J. of Biol. Chem. 264:18884-18889, 1989.
Mueckler et al., "Sequence and Structure of a Human Glucose Transporter" Science 229:941-945, 1985.
Thorens, B., "Glucose transporters in the regulation of intestinal, renal, and Liver glucose fluxes" Amer. J. of Physiol. 270:G541-G553, 1996.

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