Nucleic acid molecules encoding bacterial autoinducer...

Multicellular living organisms and unmodified parts thereof and – Method of introducing a polynucleotide molecule into or... – The polynucleotide confers pathogen or pest resistance

Reexamination Certificate

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C424S093200, C435S320100, C536S023700

Reexamination Certificate

active

10019661

ABSTRACT:
The present invention relates to isolated nucleic acid molecules encoding a bacterial autoinactivation protein and methods for increasing disease resistance and preventing or reducing bacterial damage in plants and animals. The nucleic acid that encodes the bacterial autoinducer inactivation protein can be introduced into a cell so that the bacterial autoinducer inactivation protein is expressed by the plant or animal. The nucleic acid may confer resistance to disease where the expression of pathogenic genes are regulated by autoinducers.

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Luo et al., The Antiactivatior TraM Interferes with the Autoinducer-dependent Binding of TraR to DNA by Interacting with the C-terminal Region of the Quorum-sensing Activator, The Journal of Biological Chemistry, Mar. 2000, pp. 7713-7722, vol. 275, No. 11, by The American Society for Biochemistry and Molecular Biology, Inc., printed in U.S.A.
Hwang et al., A New Regulatory Element Modulates Homoserine Lacton-Mediated Autoinduction of Ti Plasmid Conjugal Transfer, Journal of Bacteriology, Jan. 1995, p. 449-458, vol. 177, No. 2, American Society for Microbiology.

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