Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Isomerase
Reexamination Certificate
2009-12-21
2010-12-07
Fronda, Christian L (Department: 1652)
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Isomerase
C435S183000, C435S252330, C435S320100, C536S023200
Reexamination Certificate
active
07846707
ABSTRACT:
Alanine 2,3-aminomutase sequences are disclosed, as are cells having alanine 2,3-aminomutase activity and methods of selecting for such cells. Methods for producing beta-alanine, pantothenate, 3-hydroxypropionic acid, as well as other organic compounds, are disclosed.
REFERENCES:
patent: 5643758 (1997-07-01), Guan et al.
patent: 6136576 (2000-10-01), Diaz-Torres et al.
patent: 6177264 (2001-01-01), Eggeling et al.
patent: 6184006 (2001-02-01), Rieping et al.
patent: 6248874 (2001-06-01), Frey et al.
patent: 2002/0173637 (2002-11-01), Frey et al.
patent: 2003/0113882 (2003-06-01), Frey et al.
patent: 2005/0221466 (2005-10-01), Liao et al.
patent: 2008/0124785 (2008-05-01), Liao et al.
patent: WO 01/16346 (2001-03-01), None
patent: WO 01/21772 (2001-03-01), None
patent: WO 02/42418 (2002-05-01), None
patent: WO 2006/022664 (2006-03-01), None
patent: WO 2006/047589 (2006-05-01), None
patent: WO 2007/047680 (2007-04-01), None
patent: WO 2007/047773 (2007-04-01), None
Chica et al. Curr Opin Biotechnol. Aug. 2005;16(4):378-84.
Sen et al. Appl Biochem Biotechnol. Dec. 2007;143(3):212-23.
Accession O34676, published Dec. 15, 1998.
Sambrook et al. Molecular cloning A Laboratory Manual, 2nd edition, Cold Spring Harbor, N.Y. 1989, pp. 8.46-8.52.
Sambrook et al. Molecular cloning A Laboratory Manual, 2nd edition, Cold Spring Harbor, N.Y. 1989, pp. 11.2-11.19.
Accession O34676 (Dec. 15, 1998).
GenBank Accession No. AABF01000067 (Feb. 10, 2003).
Begley et al., “The Biosynthesis of Coenzyme A in Bacteria,”Vitam. Horm. 61:157-171 (2001).
Chica et al., “Semi-Rational Approaches to Engineering Enzyme Activity: Combining the Benefits of Directed Evolution and Rational Design,”Curr. Opin. Biotechnol. 16:378-384, 2005.
Cronan, “β-Alanine Synthesis inEscherichia coli,” J. Bacteriol. 141:1291-1297 (1980).
Dusch et al., “Expression ofCorynebacterium glutamicum panDGene Encoding L-Aspartate-α-Decarboxylase Leads to Pantothenate Overproduction inEscherichia coli,” Appl. Environ. Microbiol. 65:1530-1539 (1999).
Ramjee et al., “Escherichia coliL-Aspartate-α-Decarboxylase: Preprotein Processing and Observation of Reaction Intermediates by Electrospray Mass Spectrometry,”Biochem. J. 323:661-669 (1997).
Sen et al., “Developments in Directed Evolution for Improving Enzyme Functions,”Appl. Biochem. Biotechnol. 143:212-223, 2007.
Gokarn Ravi R.
Gort Steven J.
Jessen Holly J.
Liao Hans H.
Selifonova Olga
Fronda Christian L
Klarquist & Sparkman, LLP
Novozymes A/S
LandOfFree
Nucleic acid molecules encoding alanine 2,3-aminomutases does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Nucleic acid molecules encoding alanine 2,3-aminomutases, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nucleic acid molecules encoding alanine 2,3-aminomutases will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4238754