Chemistry: molecular biology and microbiology – Vector – per se
Reexamination Certificate
2011-08-23
2011-08-23
Duffy, Patricia (Department: 1645)
Chemistry: molecular biology and microbiology
Vector, per se
C435S325000, C435S252300, C435S254110, C536S023100
Reexamination Certificate
active
08003382
ABSTRACT:
Isolated nucleic acids encoding allergens of the speciesDermatophagoides pteronyssinusandDermatophagoides farinae, Der p VII and Der f VII, respectively, are disclosed. A cDNA encoding a peptide having a Der p VII activity and a predicted molecular weight of about 22, 177 daltons is described. A cDNA encoding a peptide having Der f VII activity is also described. The nucleic acids of the invention can be used as probes to detect the presence of Der p VII or Der f VII nucleic acid in a sample or for the recombinant production of peptides having a Der p VII or Der f VII activity. Peptides having a Der p VII or Der f VII activity can be used in compositions suitable for pharmaceutical administration or methods of diagnosing sensitivity to house dust mite allergens.
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Chua Kaw-Yan
Thomas Wayne R.
Duffy Patricia
Merck Patent GmbH
Perkins Coie LLP
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