Nucleic acid molecule encoding a CLASP-2 transmembrane protein

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S069100, C435S070100, C435S252300, C435S320100, C536S023100, C536S023500, C530S350000

Reexamination Certificate

active

07459308

ABSTRACT:
The present invention relates to a cell surface molecules, designated cadherin-like asymmetry proteins (“CLASPs”). In particular, it relates to CLASP-2 polynucleotides, polypeptides, fusion proteins, and antibodies. The invention also relates to methods of modulating an immune response by interfering with CLASP function.

REFERENCES:
patent: 5194596 (1993-03-01), Tischer et al.
patent: 5350836 (1994-09-01), Kopchick et al.
patent: 5965397 (1999-10-01), Jacobs et al.
patent: WO 00/20434 (2000-04-01), None
Brenner, S.E. Errors in genome function. Trends in Genetics 15(4): 132-133, 1999.
Bork et al. Go hunting in sequence databases but watch out for the traps. Trends in Genetics. 12(10): 425-427, 1996.
Wells. J.A. Additivity of mutational effects in proteins. Biochemistry 29 (37): 8509-8517, 1990.
Ngo et al. Computational complexity, protein structure prediction, and the Levinthal paradox. The Protein Folding Problem and Tertiary Structure Prediction, pp. 492-495, 1994.
Campbell et al. Totipotency of multipotentiality of cultured cells: applications and progress Theriogenology 47: 63-72, 1997.
Kaufman et al. Blood 94: 3178-3184, 1999.
Wang et al. Rapid analysis of gene expression (RAGE) facilitates universal expression profiling. Nucleic Acids Res 27(23): 4609-4618, 1999.
Wigley et al. Site-specific transgene insertion: an approach. Reprod Fertil Dev 6: 585-588, 1994.
Phillips, A., The challenge of gene therapy and DNA delivery. J Pharm Pharmacology 53: 1169-1174, 2001.
Benjamin et al. A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF. Development 125: 1591-1598, 1998.
Vukicevic et al. Induction of nephrogenic mesenchyme by osteogenic protein 1 (bone morphogenetic protein 7). Proc Natl Acad Sci USA 93: 9021-9026, 1996.
Massague et al. The TGF-beta family of growth and differentiation factors. Cell 49: 437-438, 1987.
Pilbeam et al. Comparison of the effects of various lengths of synthetic human parathyroid hormone-related peptide (hPTHrP) of malignancy on resorption and formation in organ culture. Bone 14: 717-720, 1993.
Skolnick et al. From genes to protein structure and function: novel applications of computational approaches in the genomic era. Trends in Biotech 18(1): 34-39, 2000.
Bork, A. Powers and pitfalls in sequence analysis: the 70% hurdle. Genome Res 10: 398-400, 2000.
Doerks et al. Protein annotation: detective work for function prediction. Trends in Genetics 14(6): 248-250, 1998.
Smith et al. The challenges of genome sequence annotation or “The devil is in the details”. Nature Biotech 15: 1222-1223, 1997.
Bork et al. “Go hunting in sequence databases but watch out for traps,”Trends in Genetics, 12(10):425-427, 1996.
Bork et al. “Powers and pitfalls in sequence analysis: the 70% hurdle,”Genomic Research, 10:398-400, 2000.
Brenner et al. “Errors in genome function,”Trends in Genetics, 15(4): 132-133, 1999.
Chan et al.Annual Review of Immunology, 12:555-592, 1994.
Clements et al.Annual Review of Immunology, 17:89-108, 1999.
Database EMBL, Accession No. AW959926, Jun. 8, 2000.
Database EMBL, Accession No. AI770179, Dec. 24, 1999.
Database EMBL, Accession No. AW023994, Sep. 14, 1999.
Doyle et al. “Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ,”Cell, (1996), 85: 1067.
Doerks et al. “Protein annotation: detective work for function prediction,”Trends in Genetics, 14(6): 248-250, 1998.
Drubin et al., “Origins of Cell Polarity,”Cell, (1996), vol. 84:335-344.
Dustin et al.Journal of Immunology, 157:2014, 1996.
Dustin et al.Cell, 94:667, 1998.
Dustin et al.Science. 283:649-650, 1999.
Erickson et al.J. Cell Biol., 138:589, 1997.
Geiger et al., “Spatial Relationships of Microtubule-organizing Centers and the Contact Area of Cytotoxic T Lymphocytes and Target Cells,”J. of Cell Biol., (1982), vol. 95:137-143.
Genbank Accession No. AB002297, Oct. 6, 2001.
Genbank Accession No. AB028981, Aug. 4, 1999.
Genbank Accession No. AI653716, Dec. 17, 1999.
Genbank Accession No. AF085864, Aug. 24, 1998.
Genbank Accession No. AF188523, Mar. 2, 2000.
Genbank Accession No. AI677957, Dec. 17, 1999.
Genbank Accession No. AI913163, Dec. 16, 1999.
Genbank Accession No. AL133724, Feb. 25, 2000.
Genbank Accession No. AW162535, Nov. 9, 1999.
Genbank Accession No. BE296956, Jul. 20, 2000.
Genbank Accession No. BE301939, Jul. 14, 2000.
Genbank Accession No. BE311583, Oct. 26, 2000.
Genbank Accession No. BE763461, Sep. 19, 2000.
Genbank Accession No. D86964, Oct. 6, 2001.
Genbank Accession No. X68101, Pianese et al., Feb. 24, 1999.
Genbank Accession No. Z28708, Dec. 14, 1993.
Genbank Identification No. 815795, May 18, 1995.
Genbank Identification No. 3876325, Jan. 14, 2003.
Genbank Identification No. 3882152, Jun. 16, 1999.
Genbank Identification No. 5836219, Sep. 30, 2000.
Genbank Identification No. 7243170, Mar. 14, 2000.
Genbank Identification No. 7331559, Mar. 28, 2000.
Genbank Identification No. 7711509, May 6, 2000.
Genbank Identification No. 8158664, Jun. 1, 2001.
Genbank Identification No. 9212047, Jun. 12, 2000.
Genbank Identification No. 9864498, Aug. 19, 2000.
Genbank Identification No. 9884693, Aug. 21, 2000.
Genbank Identification No. 9926440, Aug. 24, 2000.
Genbank Identification No. 9944141, Aug. 28, 2000.
Genbank Identification No. 9988160, Sep. 5, 2000.
Gergely et al., “Immunoreceptor tyrosine-based inhibition motif-bearing receptors regulate the immunoreceptor tyrosine-based activation motif-induced activation of immune competent cells,”Immunol Lett. (1999), 68: 3-15.
Gregorio et al., “Dynamic Properties of Ankyrin in T Lymphocytes: Colocalization with Spectrin and Protein Kinase Cβ,”J. Cell Biol., (1982), vol. 125:345-358.
Gruzca et al., 1999,Biochemistry38: 5024-5033.
Hanada et al., “Human homologue of the Drosophila discs large tumor suppressor binds to p56lck tyrosine kinase and Shaker type Kv1.3 potassium channel in T lymphocytes,”J Biol Chem, (1997), 272: 26899-26904.
Hung et al. “PDZ domains: structural modules for protein complex assembly,”J. Biol. Chem., 277(8): 5699-5702, 2002.
Isakov, “Immunoreceptor tyrosine-based activation motif (ITAM), a unique module linking antigen and Fc receptors to their signaling cascades,”J Leukoc Biol, (1997), 61: 6-16.
Jackson et al., “The serine protease inhibitor canonical loop conformation: examples found in extracellular hydrolases, toxins, cytokines and viral proteins,”J Mol Biol, (2000), 296: 325-34.
Kikuno et al., 1999,DNA Res. 6: 197-205.
Knudsen et al., “Four Proline-rich Sequences of the Guanine-nucleotide Exchange Factor C3G bind with Unique Specificity to the First Src Homology 3 Domain of Crk,”J. of Biol. Chem., (1994), vol. 269(52):32781-32787.
Kozak, M., 1996,Mamm. Genome7(8): 563-74.
Kupfer et al., “Small Splenic B Cells That Bind to Antigen-Specific T Helper (Th) Cells and Face the Site of Cytokine Production in the Th Cells Selectively Proliferate: Immunofluorescence Microscopic Studies of Th-B Antigen-presenting Cell Interactions,”J. Exp. Med., (1994), vol. 179:1507-1515.
Lee et al. “Activation Induces a Rapid Reorganization of Spectrin Lymphocytes,”Cell, (1988), vol. 55:807-816.
Lienard, H., 1999, J.Biol. Chem274: 32493-9.
Lupas et al., “Predicting coiled coils from protein sequences,”Science, (1991), 252: 1162-64.
Lupas et al., “Prediction and analysis of coiled-coil structures,”Methods Enzymol. 1996;266:513-25.
Mano, H., “Tec family of protein-tyrosine kinases: an overview of their structure and function,”Cytokine Growth Factor Rev., (1999), 10:267-80.
Matsui et al., “Kinetics of T-cell receptor binding to peptide/I-Ek complexes: correlation of the dissociation rate with T-cell responsiveness,” Proc Natl Acad Sci, (1994), 91(26): 12862-

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Nucleic acid molecule encoding a CLASP-2 transmembrane protein does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Nucleic acid molecule encoding a CLASP-2 transmembrane protein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nucleic acid molecule encoding a CLASP-2 transmembrane protein will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4038023

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.