Nucleic acid mediated electron transfer

Details Nucleic acid mediated electron transfer Nucleic acid mediated electron transfer

2002-10-23

2010-12-14

Mummert, Stephanie K (Department: 1637)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C422S068100, C422S050000

Reexamination Certificate

active

07851146

ABSTRACT:
The present invention provides for the selective covalent modification of nucleic acids with redox active moieties such as transition metal complexes. Electron donor and electron acceptor moieties are covalently bound to the ribose-phosphate backbone of a nucleic acid at predetermined positions. The resulting complexes represent a series of new derivatives that are bimolecular templates capable of transferring electrons over very large distances at extremely fast rates. These complexes possess unique structural features which enable the use of an entirely new class of bioconductors and photoactive probes.

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