Nucleic acid material amplification and detection without washin

Details Nucleic acid material amplification and detection without washin Nucleic acid material amplification and detection without washin

1992-11-20

1995-06-06

Parr, Margaret

Chemistry: molecular biology and microbiology

Apparatus

Including measuring or testing

206223, 206569, 422 57, 422 58, 435 6, 435 912, 435291, C12M 100

Patent

active

054222710

ABSTRACT:
A device and method are disclosed for amplifying and detecting nucleic acid material. The device and method use a label and signalling material responsive to the label to produce a detectable signal. A surprising result of the method and device is that at least one of the wash steps heretofore required has been eliminated without substantially adversely affecting the results.

REFERENCES:
patent: 5147609 (1992-09-01), Grenner
Whessell et al, Comparison of Three Nonradioisotopic Polymerase Chain Reaction-Based Methods for Detection of Human Immunodeficiency Virus Type I. J. Clin. Microbiology, vol. 30, pp. 845-853 (Apr. 1992).

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