Nucleic acid ligands of tissue target

Details Nucleic acid ligands of tissue target Nucleic acid ligands of tissue target

1997-11-21

2000-10-03

Zitomer, Stephanie

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 912, 536 243, 536 2431, 536 254, C12Q 168, C12P 1934, C07H 2102, C07H 2104

Patent

active

061271195

ABSTRACT:
This invention discloses high-affinity oligonucleotide ligands to complex tissue targets, specifically nucleic acid ligands having the ability to bind to complex tissue targets, and the methods for obtaining such ligands. Tissue targets comprise cells, subcellular components, aggregates or cells, collections of cells, and higher ordered structures. Specifically, nucleic acid ligands to blood vessels are described.

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