Nucleic acid ligand inhibitors to DNA polymerases

Details Nucleic acid ligand inhibitors to DNA polymerases Nucleic acid ligand inhibitors to DNA polymerases

1995-06-07

1997-12-02

Zitomer, Stephanie W.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435810, C12P 1934

Patent

active

056935021

ABSTRACT:
This invention discloses high-affinity oligonucleotide ligands to the thermostable Taq polymerase and Tth polymerase. Specifically, this invention discloses DNA ligands having the ability to bind to the Taq and Tth polymerases and the methods for obtaining such ligands. The ligands are capable of inhibiting polymerases at ambient temperatures.

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