Nucleic acid injected into hepatic vein lumen

Details Nucleic acid injected into hepatic vein lumen Nucleic acid injected into hepatic vein lumen

2006-10-10

2009-06-16

Li, Q. Janice (Department: 1633)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C435S069100, C435S455000

Reexamination Certificate

active

07547683

ABSTRACT:
Processes are described for obtaining high levels of gene expression in primates after injection of nucleic acid to the liver via the lumen of the hepatic vein. The described process results in high level of gene expression with transient increases in liver enzymes.

REFERENCES:
patent: 6265387 (2001-07-01), Wolff et al.
patent: 6627616 (2003-09-01), Monahan et al.
patent: 7144869 (2006-12-01), Wolff et al.

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