Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1995-05-05
1998-08-11
Knode, Marian C.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 71, 435 75, 435 79, 436518, C12Q 168, G01N 33536
Patent
active
057926069
ABSTRACT:
The application describes homogeneous assays for determining ligands. A sample is contacted with a labeled substance P.sub.2 and receptor R. The receptor R consists of one molecule of P.sub.1, which monovalently and specifically binds to P.sub.2, and one molecule for R.sub.1, which binds to the ligand of interest. Complexes of P.sub.1, P.sub.2, R.sub.1 and ligand form, and are determined. R.sub.1 must be a nucleic acid molecule.
REFERENCES:
patent: 4134792 (1979-01-01), Bogulaski et al.
patent: 4711955 (1987-12-01), Ward et al.
patent: 5126241 (1992-06-01), Schenk
patent: 5437981 (1995-08-01), Deger et al.
patent: 5482867 (1996-01-01), Barrett et al.
patent: 5484701 (1996-01-01), Cocuzza et al.
Kessler, "The digoxigenin:anti-digoxigenic (DIG) technology--a survey on the concept and realization of a novel bioanalytical indicator system", Mol. Cell. Probes 5, 161-205 (1991).
Kohler, S., et al., "Toward Routine Diagnosis of Hepatitis B Virus DNA", Clin. Chem. 39, p. 1185, Abstr. No. 0306, 1993.
Deger Arno
Schenk Roland
Boehringer Mannheim GmbH
Knode Marian C.
Wortman Donna C.
LandOfFree
Nucleic acid hybridization based assay for determining a substan does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Nucleic acid hybridization based assay for determining a substan, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nucleic acid hybridization based assay for determining a substan will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-387858