Nucleic acid hybridization assay for hepatitis B virus DNA

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

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435 6, 435243, 4353201, 435948, 436501, 436811, 536 231, 536 241, 536 243, 536 2431, 536 2432, 536 2433, 935 6, 935 9, 935 77, 935 78, C12Q 168

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056143621

ABSTRACT:
Linear or branched oligonucleotide multimers useful as amplifiers in biochemical assays which comprise (1) at least one first single-stranded oligonucleotide unit that is complementary to a single-stranded oligonucleotide sequence of interest, and (2) a multiplicity of second single-stranded oligonucleotide units that are complementary to a single-stranded labeled oligonucleotide. Amplified sandwich nucleic acid hybridizations and immunoassays using the multimers are exemplified.

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