Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for...
Reexamination Certificate
2007-10-23
2007-10-23
Steadman, David J. (Department: 1656)
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
C435S069200, C435S228000, C435S191000, C435S320100, C435S471000, C435S252330, C435S252340, C435S252500, C435S252350, C435S252200, C435S255200, C435S256100, C435S256300, C435S255600, C435S254400, C435S253500, C435S252600, C435S183000
Reexamination Certificate
active
11601230
ABSTRACT:
The invention relates to the isolation, sequencing, and recombinant expression of genes encoding either a nitrile hydratase (NHase) or amidase (Am) fromComamonas testosteroni5-MGAM-4D, where the NHase is useful for catalyzing the hydration of nitrites to the corresponding amides, and the amidase is useful for hydrolysis of amides to the corresponding carboxylic acids. Also provided are transformed host cells containing polynucleotides for expressing the nitrile hydratase or amidase enzymes fromComamonas testosteroni5-MGAM-4D.
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DiCosimo Robert
Fallon Robert D.
Gavagan John E.
Payne Mark S.
E.I. du Pont de Nemours and Company
Gebreyesus Kagnew
Steadman David J.
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