Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing nitrogen-containing organic compound
Reexamination Certificate
2007-11-13
2007-11-13
Bragdon, Kathleen Kerr (Department: 1656)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing nitrogen-containing organic compound
C435S228000, C435S252000, C435S254200, C435S254210, C435S254230, C435S254300, C435S069100, C536S023200
Reexamination Certificate
active
11601186
ABSTRACT:
The invention relates to the isolation, sequencing, and recombinant expression of genes encoding either a nitrile hydratase (NHase) or amidase (Am) fromComamonas testosteroni5-MGAM-4D, where the NHase is useful for catalyzing the hydration of nitriles to the corresponding amides, and the amidase is useful for hydrolysis of amides to the corresponding carboxylic acids. Also provided are transformed host cells containing polynucleotides for expressing the nitrile hydratase or amidase enzymes fromComamonas testosteroni5-MGAM-4D.
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DiCosimo Robert
Fallon Robert D.
Gavagan John E.
Payne Mark S.
Bragdon Kathleen Kerr
E. I. du Pont de Nemours and Company
Gebreyesus Kagnew
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