Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...
Patent
1994-04-14
1997-08-19
Horlick, Kenneth R.
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
4352523, 4353201, 435366, 536 235, 536 2431, C07H 2104
Patent
active
056587848
ABSTRACT:
The invention features an isolated nucleic acid hybridizable with the complement of the coding strand nucleic acid sequence presented in SEQ ID NO:1, and encoding a protein that is necessary for adenovirus transformation of a mammalian cell. The encoded protein, p300, cooperates with adenovirus E1A (Early-region 1A) proteins to establish the transformed state.
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Eckner Richard
Ewen Mark
Livingston David
Dana-Farber Cancer Institute Inc.
Horlick Kenneth R.
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