Multicellular living organisms and unmodified parts thereof and – Plant – seedling – plant seed – or plant part – per se – Higher plant – seedling – plant seed – or plant part
Reexamination Certificate
2005-05-10
2005-05-10
Kubelik, Anne (Department: 1638)
Multicellular living organisms and unmodified parts thereof and
Plant, seedling, plant seed, or plant part, per se
Higher plant, seedling, plant seed, or plant part
C800S279000, C435S320100, C435S235100, C424S093200, C424S093210, C536S023500
Reexamination Certificate
active
06891085
ABSTRACT:
The methods and compositions of the present invention find use in impacting microbial pathogens and in enhancing disease resistance to pathogens, particularly by plants. The compositions of the invention include nucleic acid molecules encoding Fus6 polypeptides derived fromAgrotis ipsilonthat possess antimicrobial properties, particularly fungicidal properties. Further provided are plant cells plants, and seed thereof, transformed with the nucleic acid molecules of the invention so as to confer disease resistance on the plant.
REFERENCES:
patent: 5436392 (1995-07-01), Thomas et al.
patent: 5597945 (1997-01-01), Jaynes et al.
patent: 5597946 (1997-01-01), Jaynes et al.
patent: 5614395 (1997-03-01), Ryals et al.
patent: 5811654 (1998-09-01), Jaynes et al.
patent: 6100453 (2000-08-01), Aldwinckle et al.
patent: 20020166142 (2002-11-01), Mitsuhara et al.
patent: WO-9405787 (1994-03-01), None
patent: WO 9501430 (1995-01-01), None
patent: WO 9859048 (1998-12-01), None
patent: WO-9924594 (1999-05-01), None
patent: WO 9953053 (1999-10-01), None
patent: WO-9967357 (1999-12-01), None
Chakrabarti et al, 2003, Planta 216:587-596.*
Ponti et al, 2003, Biochem. J. 370:121-127.*
Bulet et al, 1999, Devel. Comp. Immunol. 23:329-344.*
Bulet et al, 2003, “Antimicrobial peptides in insect immunity” In: Infectious Disease: Innate Immunity, Ezekowitz et al, eds., Humana press, Totowa, NJ, pp. 89-107.*
Hetru et al, 1998, “Antimicrobial peptides from insects” In: Molecular mechanisms of immune responses in insects, Frey et al, eds., p. 40-66.*
Mitsuhara et al, 2000, Mol. Plant-Microbe Interact. 13:860-868.*
Lazar et al, 1988, Mol. Cell. Biol. 8:1247-1252.*
Hill et al, 1998, Biochem. Biophys. Res. Comm. 244:573-577.*
Pang et al, 1992, Gene 116:165-172.*
De Bolle et al, 1996, Plant Mol. Biol. 31:993-1008.*
Hightower et al, 1994, Plant Cell Rep. 13:295-299.*
AlIefs et al, 1995, Am. Potato J. 72:437-445.*
Okamoto et al , 1998, Plant Cell Physiol. 39:57-63.*
Cavallarin, L., et al., “Cecropin A-Derived Peptides Are Potent Inhibitors of Fungal Plant Pathogens,”Molecular Plant-Microbe Interactions, 1998, pp. 218-227, vol. 11(3), The American Phytopathological Society, USA.
Choi, C., et al., “Antibacterial Properties and Partial cDNA Sequences of Cecropin-Like Antibacterial Peptides From the Common Cutworm,Spodoptera litura,” Comparative Biochemistry and Physiology, Part C., 2000, pp. 287-297, vol. 125, Elsevier Science Inc.
Destéfano-Beltrán, L., “Using Genes Encoding Novel Peptides and Proteins to Enhance Disease Resistance in Plants,”Biotechnology in Plant Disease Control, 1993, pp. 175-189.
Rao, A.G., “Antimicrobial Peptides,”Molecular Plant-Microbe Interactions, 1995, pp. 6-13, vol. 8(1), The American Phytopathological Society, USA.
GenBank Report for Accession No. AF226857, Direct Submission on Jan. 19, 2000.
GenBank Report for Accession No. BI262536, Direct Submission on Jul. 17, 2001.
GenBank Report for Accession No. BI262658, Direct Submission on Jul. 17, 2001.
GenBank Report for Accession No. U23831, Direct Submission on Mar. 31, 1995.
GenBank Report for Accession No. BI262643, Direct Submission on Jul. 17, 2001.
GenBank Report for Accession No. BI262626, Direct Submission on Jul. 17, 2001.
GenBank Report for Accession No. BI26271 I, Direct Submission on Jul. 17, 2001.
GenBank Report for Accession No. BI262708, Direct Submission on Jul. 17, 2001.
Boman, H., et al., “On The Primary Structures of Lysozyme, Cecropins and Attacins from Hyalophora Cecropia,”Developmental and Comparative Immunology, 1985, pp. 551-558, vol. 9.
Butler, M., et al., “The Aminopeptidase N-encoding pepN Gene ofStreptomyces lividians66,”Gene, 1994, pp. 115-119, vol. 141(1), Elsevier Science B.V.
Chowdhury, S., et al., “cDNA Cloning and Gene Expression of Lebocin, A Novel Member of Antibacterial Peptides from the Silkworm,Bombyx mori,” Biochemical and Biophysical Research Communications, Sep. 1995, pp. 271-278, vol. 214(1), Academic Press, Inc.
Dushay, M., et al., “Twin attacin Antibacterial Genes ofDrosophila melanogaster,” Gene, 2000, pp. 49-57, vol. 246, Elsevier Science B.V.
Engstrom, A., et al., “Insect Immunity. The Primary Structure of the Antibacterial Protein attacin F and its Relation to Two Native Attacins fromHyalophora cecropia,” The EMBO Journal, 1984, pp. 2065-2070, vol. 3(9).
Engstrom, P., et al., “The Antibacterial Effect of Attacins from the Silk MothHyalophora cecropiais Directed Against the Outer Membrane ofEscherichia coli,” The EMBO Journal, 1984, pp. 3347-3351, vol. 3(13).
Frobius, A., et al., “Isolation and Characterization of Novel Inducible Serine Protease Inhibitors from Larval Hemolymph of the Greater Wax MothGalleria mellonella,” European Journal of Biochemistry, 2000, pp. 2046-2053, vol. 267, FEBS.
Furukawa, S., et al., “A Novel Member of Lebocin Gene Family from the Silkworm,Bombyx mori,” Biochemical and Biophysical Research Communications, 1997, pp. 769-774, vol. 238(3), Academic Press.
Gura, T., “Innate Immunity: Ancient System Gets New Respect,”Science, Mar. 2001, pp. 2068-2071, vol. 291.
Hara, S., and M. Yamakawa, “A Novel Antibacterial Peptide Family Isolated from the Silkworm,Bombyx mori,” Biochem. J., 1995, pp. 651-656, vol. 310(2), The Biochemical Society. Great Britain.
Ko, K., “Using Antimicrobial Proteins to Enhance Plant Resistance,”APSnet Feature(www.apsnet.org Online Publication), 2000, The American Phytopathological Society, USA.
Kockum, K., et al., “Insect Immunity. Isolation and Sequence of Two cDNA Closes Corresponding to Acidic and Basic Attacins fromn Hyalophora,”EMBO Journal, 1984, pp. 2071-2075. vol. 3(9).
Lamberty, M., et al., “Insect Immunity: Isolation from the LepidopteranHeliothis virescensof a Novel Insect Defensin with Potent Antifungal Activity,”The Journal of Biological Chemistry, 1999, pp. 9320-9326, vol. 274(14), The American Society for Biochemistry and Molecular Biology, Inc., USA.
Maes, M., et al., “Lower Serum Activity of Prolyl Endopeptidase in Fibromyalgia is Related to Severity of Depressive Symptoms and Pressure Hyperalgesia,”Psychological Medicine, 1998, pp. 957-965. vol. 28(4), Cambridge University Press, United Kingdom.
Sasaki, T., “Amino-Acid Sequences of Two Basic Chymotrypsin Inhibitors from Silkworm Larval Hemolyrnph,”Biol. Chem. Hoppe-Seyler, Nov. 1988, pp. 1235-1241, vol. 369.
Schaffrath, U., et al., “Constitutive Expression of the Defense-Related Rirlb Gene in Transgenic Rice Plants Confers Enhanced Resistance to the Rice Blast FungusMagnaporthe grisea,” Plant Molecular Biology, 2000, pp. 59-66, vol. 43, Kluwer Academic Publishers, Netherlands.
Sharma, A., et al., “Transgenic Expression of Cecropin B, an Antibacterial Peptide fromBombyx mori, Confers Enhanced Resistance to Bacterial Leaf Blight in Rice,”FEBS Letters, 2000, pp. 7-11, vol. 484, Elsevier Science B.V.
Sun, S., et al., “Structure and Expression of the Attacin Genes inHyalophora cecropia,” Eur. J. of Biochem., 1991, pp. 247-254, vol. 196(1), Springer International.
Thevissen, K., et al., “Fungal Membrane Responses Induced by Plant Defensins and Thionins,”The Journal of Biological Chemistry, Jun. 1996, pp 15018-15025, vol. 271(25), The American Society for Biochemistry and Molecular Biology, Inc., USA.
Toide, K., et al., “A Novel Prolyl Endopeptidase Inhibitor, JTP-4819 Its Behavorial and Neurochemical Properties for the Treatment of Alzheimer's Disease,”Reviews in the Neurosciences, 1998, pp. 17-29, vol. 9(1), Freund & Pettman, U.K.
Tsuzurahara, S., et al., “Detection of MAGE-4 Protein in the Sera of Patients with Hepatitis-C Virus-Associated Hepatocellular Carcinoma and Liver Cirrhosis,”Jpn. J. Cancer Res., Sep. 1997, pp. 915-918, vol. 88(9).
Uttenweiler-Joseph, S., et al., “Differential Display
Altier Daniel J.
Herrmann Rafael
Lu Albert L.
McCutchen Billy F.
Presnail James K.
Alston & Bird LLP
E.I. du Pont de Nemours and Company
Kubelik Anne
Pioneer Hi-Bred International , Inc.
LandOfFree
Nucleic acid encoding the FUS6 antimicrobial polypeptide of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Nucleic acid encoding the FUS6 antimicrobial polypeptide of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nucleic acid encoding the FUS6 antimicrobial polypeptide of... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3388989